Results 21 to 30 of about 409,945 (260)
Enhanced cultivation of chicken primordial germ cells
Scientific Reports, 2023 The cultivation and expansion of chicken primordial germ cells (cPGCs) are of critical importance for both biotechnological applications and the management of poultry genetic biodiversity.
Nima Dehdilani +8 more
doaj +1 more source
NMDAR mediated dynamic changes in m6A inversely correlates with neuronal translation
Scientific Reports, 2022 Epitranscriptome modifications are crucial in translation regulation and essential for maintaining cellular homeostasis. N6 methyladenosine (m6A) is one of the most abundant and well-conserved epitranscriptome modifications, which is known to play a ...
Naveen Kumar Chandappa Gowda +4 more
doaj +1 more source
Archives of Neurology, 2008 Mutations that cause autosomal recessive primary microcephaly (MCPH), including MCPH1 through MCPH6, have provided insight into the normal programming that directs brain growth and defines ultimate brain size. The common denominator in these mutations is that they all manifest within neural stem and progenitor cells, decreasing their numbers at various
openaire +2 more sources
Translationally Relevant Magnetic Resonance Imaging Markers in a Ferret Model of Closed Head Injury
Frontiers in Neuroscience, 2022 Pre-clinical models of traumatic brain injury (TBI) have been the primary experimental tool for understanding the potential mechanisms and cellular alterations that follow brain injury, but the human relevance and translational value of these models are ...
Elizabeth B. Hutchinson +18 more
doaj +1 more source
Comparison between auditory steady-state responses and pure-tone audiometry [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. A more recent method, the auditory steadystate response (ASSR), has become more and more important test method due to difference that was found in previous investigations between hearing thresholds determined by the ASSR and the pure-tone
Komazec Zoran +5 more
doaj +1 more source
Case Reports in Neurology, 2023 Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disease of the central nervous system that predominantly affects the brainstem. Apart from corticosteroids, there are few reported
Takumi Tsuchida +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Nature CommunicationsPluripotent stem cells have long been used to produce knockout mice via germline chimera technology. However, aside from the rat, this approach has not been successfully applied to other mammals.
Hong-Thu Pham +18 more
doaj +1 more source
Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation
EBioMedicine, 2015 Although deep brain stimulation (DBS) shows promising efficacy as a therapy for intractable depression, the neurobiological bases underlying its therapeutic action remain largely unknown.
A. Etiévant +17 more
doaj +1 more source