Results 21 to 30 of about 447,656 (309)

Drosophila Neural Stem Cells in Brain Development and Tumor Formation [PDF]

, 2014
Neuroblasts, the neural stem cells in Drosophila, generate the complex neural structure of the central nervous system. Significant progress has been made in understanding the mechanisms regulating the self-renewal, proliferation, and differentiation in ...
Reichert, Heinrich, Jiang, Yanrui
core   +1 more source

Blink reflex in idiopathic intracranial hypertension patients [PDF]

Egyptian Journal of Medical Research, 2022
The goal of our study was to clarify the possible effect of increased intracranial pressure on electrophysiological blink reflex in idiopathic intracranial hypertension (IIH) pateints .
Hanan Hosny, Mohamed Mabrouk, Dalia Gamal, Rehab Elanwar   +3 more
doaj   +1 more source

Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting [PDF]

, 2012
INTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only
Van Der Linden, Anne-Marie, Van der Linden, Annemie, Herman Goossens, Annemie Van der Linden, Berneman, Zwi Nisan, De Vocht, Nathalie, Debbie Le Blon, Hoornaert, Chloé, Kristien Reekmans, Berneman, Zwi, Jasmijn Daans, Reekmans, Kristien, Nathalie De Vocht, Ponsaerts, Peter, Fransen, Erik, Chloé Hoornaert, Hoornaert, Chlo\ue9, Erik Fransen, Praet, Jelle, Le Blon, Debbie, Zwi Berneman, Goossens, Herman, Peter Ponsaerts, Jelle Praet, Daans, Jasmijn   +24 more
core   +1 more source

Exploring the Acquisition and Production of Grammatical Constructions Through Human-Robot Interaction with Echo State Networks

Frontiers in Neurorobotics, 2014
One of the principal functions of human language is to allow people to coordinate joint action. This includes the description of events, requests for action, and their organization in time.
Xavier eHinaut, Xavier eHinaut, Maxime ePetit, Maxime ePetit, Grégoire ePointeau, Grégoire ePointeau, Peter F Dominey, Peter F Dominey, Peter F Dominey   +8 more
doaj   +1 more source

Potentiel des organoïdes cérébraux comme modèles d’étude des neuropathologies chez les animaux domestiques

INRAE Productions Animales, 2023
Le cerveau est un organe complexe et tout modèle pour l'étudier dans ses aspects normaux et pathologiques devient un outil de choix en neurobiologie. La maîtrise et la diffusion de protocoles permettant le développement d'organoïdes cérébraux ont ouvert
Bertrand PAIN , Noémie AURINE, Théo LA ROSA, Camille BAQUERRE, Muriel COULPIER   +4 more
doaj   +1 more source

Neural stem cells in Drosophila : molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation [PDF]

, 2012
Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors.
Heinrich Reichert, Reichert, Heinrich, Saini, Nidhi, Nidhi Saini   +3 more
core   +1 more source

Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice

Nature Communications, 2016
Rett syndrome is a neurodevelopmental disorder caused by mutations in Mecp2. Here the authors show that Mecp2 loss-of-function leads to upregulation of the NF-κB pathway, and that reducing NF-κB signalling ameliorates phenotypes of Mecp2-null mice, thus ...
Noriyuki Kishi, Jessica L. MacDonald, Julia Ye, Bradley J. Molyneaux, Eiman Azim, Jeffrey D. Macklis   +5 more
doaj   +1 more source

NMDAR mediated translation at the synapse is regulated by MOV10 and FMRP

Molecular Brain, 2019
Protein synthesis is crucial for maintaining synaptic plasticity and synaptic signalling. Here we have attempted to understand the role of RNA binding proteins, Fragile X Mental Retardation Protein (FMRP) and Moloney Leukemia Virus 10 (MOV10) protein in ...
Preeti Madhav Kute, Sarayu Ramakrishna, Nagammal Neelagandan, Sumantra Chattarji, Ravi. S. Muddashetty   +4 more
doaj   +1 more source

Radial Migration Dynamics Is Modulated in a Laminar and Area-Specific Manner During Primate Corticogenesis

Frontiers in Cell and Developmental Biology, 2020
The orderly radial migration of cortical neurons from their birthplace in the germinal zones to their final destination in the cortical plate is a prerequisite for the functional assembly of microcircuits in the neocortex.
Veronique Cortay, Delphine Delaunay, Dorothée Patti, Elodie Gautier, Nathalie Doerflinger, Pascale Giroud, Kenneth Knoblauch, Cyril Huissoud, Cyril Huissoud, Henry Kennedy, Henry Kennedy, Colette Dehay   +11 more
doaj   +1 more source

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns

Molecular Autism, 2020
Background Fragile X syndrome (FXS), a neurodevelopmental disorder, is a leading monogenetic cause of intellectual disability and autism spectrum disorder.
Shreya Das Sharma, Rakhi Pal, Bharath Kumar Reddy, Bhuvaneish T. Selvaraj, Nisha Raj, Krishna Kumar Samaga, Durga J. Srinivasan, Loren Ornelas, Dhruv Sareen, Matthew R. Livesey, Gary J. Bassell, Clive N. Svendsen, Peter C. Kind, Siddharthan Chandran, Sumantra Chattarji, David J. A. Wyllie   +15 more
doaj   +1 more source