2008 Progress Report on Brain Research [PDF]
, 2008 Highlights new research on various disorders, nervous system injuries, neuroethics, neuroimmunology, pain, sense and body function, stem cells and neurogenesis, and thought and memory.
Eve Marder +3 more
core
Locally induced neural stem cells/pluripotent stem cells for in vivo cell replacement therapy [PDF]
, 2008 : Neural stem cells hold the key to innovative new treatments for age-associated degeneration and traumatic injury to the brain and spinal cord. We hypothesized that the in vivo induced pluripotent stem cells or neural stem cells through 'forced gene ...
Arias-Carrión, O, Yuan, TF
core +3 more sources
Multiscale Autoencoder with Structural-Functional Attention Network for Alzheimer's Disease Prediction [PDF]
arXiv, 2022 The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information and discover disease mechanisms from various magnetic resonance images (MRI). In this paper, we propose a simple but
arxiv
Hypothesis to explain yawning, cortisol rise, brain cooling and motor cortex involvement of involuntary arm movement in neurologically impaired patients. [PDF]
, 2017 Association between the hormone cortisol and yawning has been found. The Thompson Cortisol Hypothesis proposed a link between yawning and rises in cortisol with further recent evidence from neuroscience showing communication between the motor
Thompson, Simon
core +1 more source
OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma
Nature CommunicationsFunctional cellular heterogeneity in tumours often underlies incomplete response to therapy and relapse. Previously, we demonstrated that the growth of the paediatric brain malignancy, sonic hedgehog subgroup medulloblastoma, is rooted in a dysregulated ...
Kinjal Desai +18 more
doaj +1 more source
Cell Reports, 2023 Summary: Investigation of translation in rare cell types or subcellular contexts is challenging due to large input requirements for standard approaches. Here, we present “nanoRibo-seq” an optimized approach using 102- to 103-fold less input material than
John E. Froberg +2 more
doaj
Frontiers in Molecular Neuroscience, 2019 Dendritic growth and branching are highly regulated processes and are essential for establishing proper neuronal connectivity. There is a critical phase of early dendrite development when these are heavily regulated by external cues such as trophic ...
Sreenath Ravindran +3 more
doaj +1 more source
Comparison between auditory steady-state responses and pure-tone audiometry [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. A more recent method, the auditory steadystate response (ASSR), has become more and more important test method due to difference that was found in previous investigations between hearing thresholds determined by the ASSR and the pure-tone
Komazec Zoran +5 more
doaj +1 more source
Comparison of atlas-based and neural-network-based semantic segmentation for DENSE MRI images [PDF]
arXiv, 2021 Two segmentation methods, one atlas-based and one neural-network-based, were compared to see how well they can each automatically segment the brain stem and cerebellum in Displacement Encoding with Stimulated Echoes Magnetic Resonance Imaging (DENSE-MRI) data. The segmentation is a pre-requisite for estimating the average displacements in these regions,
arxiv
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' [PDF]
, 2005 We combined large-scale mRNA expression analysis and gene mapping to identify genes and loci that control hematopoietic stem cell (HSC) function. We measured mRNA expression levels in purified HSCs isolated from a panel of densely genotyped recombinant ...
A Scherer +24 more
core +2 more sources