Results 61 to 70 of about 933,949 (357)

Successful treatment with cladribine of Erdheim-Chester disease with orbital and central nervous system involvement developing after treatment of langerhans cell histiocytosis [PDF]

Vojnosanitetski Pregled, 2016
Introduction. Erdheim-Chester disease (ECD) is a rare, systemic form of non-Langerhans cell histiocytosis of the juvenile xantho-granuloma family with characteristic bilateral symmetrical long bone osteosclerosis, associated with ...
Perić Predrag, Antić Branislav, Knežević-Ušaj Slavica, Radić-Tasić Olga, Radovinović-Tasić Sanja, Vasić-Vilić Jasenka, Sekulović Leposava, Tarabar Olivera, Tukić Ljiljana, Jovandić Stevo, Magić Zvonko   +10 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts

Epigenetics & Chromatin
Post-translational modifications of histone H3 on lysine 9, specifically acetylation (H3K9ac) and tri-methylation (H3K9me3), play a critical role in regulating chromatin accessibility.
Wilhelm Bouchereau, Hong-Thu Pham, Worawalan Samruan, Van-Hong Vu, Thierry Joly, Marielle Afanassieff, Pierre Savatier, Rangsun Parnpai, Nathalie Beaujean   +8 more
doaj   +1 more source

Age correlation of cerebral corpus callosum and brainstem area indicators

Сибирский научный медицинский журнал, 2022
Since aging is characterized by morphofunctional changes in humans, longevity leads to an increase in age-associated features of their bodies. Aim of the study was to carry out a comparative analysis of the cerebral corpus callosum and brainstem area in ...
A. A. Balandin, G. S. Yurushbaeva, I. A. Balandina   +2 more
doaj   +1 more source

Improvise the working condition at Kilang Beras Jelapang Selatan (M) Sdn. Bhd. [PDF]

, 2020
Kilang Beras Jelapang Selatan (M) Sdn. Bhd. or known as KBJS was established on 11th March 1988. KBJS is located at industrial area, Batu 2 ¾ Jalan Salleh,8400, Muar, Johor. The size of the factory is more than 2.5 acre.
Mahmood, Salwa, Ngadiman, Nor Hasrul Akhmal, Tajurahim, Nurul Ainina Nadhirah   +2 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Subacute brain-stem encephalitis [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1974
A 65 year old man developed progressive signs of pontine and medullary dysfunction with striking bilateral paralysis of lateral gaze, dysarthria, dysphagia, and ataxia. A respiratory death occurred seven months from the onset. Pathological examination revealed focal brain-stem changes of perivascular lymphocytic cuffing, microglial infiltration, glial ...
S G, Waxman, T D, Sabin, L J, Embree
openaire   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The prefrontal operculum, a human-specific hub for the cognitive control of speech

Communications Biology
Current theories fail to explain why the ability to control speech is unique to humans. We recently identified one unique feature in the human frontal cortex that may hold the key to this question: the Prefrontal Operculum (PFO).
Charles Verstraete, Elsa Lazzaro, Delphine Autran-Clavagnier, Manon Dirheimer, Fadila Hadj-Bouziane, Franck Lamberton, Kep Kee Loh, Emmanuel Procyk, Charles R. E. Wilson, Camille Giacometti, Céline Amiez   +10 more
doaj   +1 more source