Results 121 to 130 of about 3,399,085 (314)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
The Ability of the Gliadel® Wafer to Control the Malignant Brain Tumor；Preliminary Report [PDF]
, 2007 Introduction：Adjuvant systemic chemotherapy increases survival for malignant glioma patients. However, it is unable to effectively cross the blood-brain barrier and have unacceptable systemic toxicities, and the short exposure time of tumor tissue to ...
김동석 +5 more
core
Pharmacotherapy of brain tumors
, 2023 A brain tumor refers to an abnormal growth or mass of cells within the brain or its surrounding tissues. These tumors can be benign, or malignant and may originate from the brain itself (primary brain tumors) or spread from other parts of the body ...
Cheong, Yoonho
core
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Scientific ReportsProtoporphyrin IX (PPIX) is a fluorescent metabolite in the heme biosynthesis pathway, and cancer cells accumulate it when 5-aminolevulinic acid (5-ALA), a precursor, is administered. In the U.S., 5-ALA is approved for visualizing high-grade gliomas (HGG)
William Knight +4 more
doaj +1 more source
HYDATID TUMORS OF THE BRAIN. [PDF]
Journal of the American Medical Association, 1885 Sir: —Allow me to call attention to two points in the paper by Dr. R. Harvey Reed, on "Hydatid Tumor of the Brain," published in theJournalof July 4th. (1) The term hydatid tumor should be, and usually is, limited to the echinococcus cyst, the larvae of the Taenia echinococcus or Hydatid tapeworm.
openaire +2 more sources
From homogeneous to fractal normal and tumorous microvascular networks in the brain [PDF]
, 2006 We studied normal and tumorous three-dimensional (3D) microvascular networks in primate and rat brain. Tissues were prepared following a new preparation technique intended for high-resolution synchrotron tomography of microvascular networks.
Plouraboué, Franck +5 more
core +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier +3 more
wiley +1 more source