Results 211 to 220 of about 2,536,308 (310)

A novel hybrid transformer-based framework (H-ConvNeXt-Swin) to classify brain tumors using MRI. [PDF]

Sci Rep
Abdellatef E, Al-Makhlasawy RM, El-Mawla NA, Shalaby WA.   +3 more
europepmc   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

Advanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu   +27 more
wiley   +1 more source

Current management of low-grade, epilepsy-associated brain tumors in Europe. [PDF]

Epilepsia
Arzimanoglou A, Tchaicha S, Harrington BT, Mühlebner A, Najm I, Blümcke I.   +5 more
europepmc   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Clinical trial design for primary brain tumors: a problem-based framework for neuro-oncology practice. [PDF]

Front Oncol
Gómez-Puerto D, Yaringaño J, Di Muzio A, Mirallas O, Vieito M.   +4 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Evaluating "brain permeability": A critical issue for the development of therapeutic agents for primary and metastatic brain tumors. [PDF]

Neuro Oncol
Grossman SA, Barone A, Strowd RE, Rais R, Duke E, Wearne E, Price LSL, Hendrix C, Schreck KC, Lesser G, Sanai N, Romo C, Portnow J, Blakeley JO, Kamson DO, Nabors B, Searson P, Sarkaria JN, Peereboom D, Schiff D, Prowell T, Elmquist WF.   +21 more
europepmc   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Response to letter to the editor regarding “electrophysiological monitoring of the trigeminal nerve sensory root using sensory-masseter response for microvascular decompression in trigeminal neuralgia”

Acta Neurochirurgica
Weichao Jiang, Xiyao Liu
doaj   +1 more source

AI-Based Methods in Neuropathology for Diagnosis and Treatment of Brain Tumors. [PDF]

Eur J Neurol
Roetzer-Pejrimovsky T, Amberg N, Widhalm G, Höftberger R.   +3 more
europepmc   +1 more source