Results 61 to 70 of about 2,536,308 (310)

Evaluation of Adoptive T Cell Therapy and Oncolytic Virotherapy for Treatment of Brain Tumors [PDF]

, 2010
Item reinstated by Sarah Shreeves (sshreeve@illinois.edu) on 2013-01-22T11:00:26Z Item was in collections: University of Illinois Dissertations and Theses (ID: 204) Neuroscience Program Dissertations (ID: 630) No.
Thomas, Diana L.
core  

Child-related characteristics predicting subsequent health-related quality of life in 8- to 14-year-old children with and without cerebellar tumors: a prospective longitudinal study

, 2014
BackgroundWe identified child-related determinants of health-related quality of life (HRQoL) in children aged 8–14 years who were treated for 2 common types of pediatric brain tumors.
Kennedy, Colin R., Christina Liossi, Culliford, David, Colin R. Kennedy, Kim S. Bull, David Culliford, Liossi, Christina, Peacock, Janet L., Janet L. Peacock, Bull, Kim S.   +9 more
core   +1 more source

Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy [PDF]

, 2009
Background: Glioblastoma is the most frequent and most malignant primary brain tumor with a poor prognosis. The translation of therapeutic strategies for glioblastoma from the experimental phase into the clinic has been limited by insufficient animal ...
Oleg Tsinkalovsky, Euskirchen Philipp, Tsanan Giroglou, Huszthy, Peter C., Giroglou Tsanan, Skaftnesmo, Kai Ove, Miletic, Hrvoje, Miletic Hrvoje, Peter C Huszthy, Kai Ove Skaftnesmo, Tsinkalovsky Oleg, von Laer Dorothee, Euskirchen, Philipp, Dorothee von Laer, Hrvoje Miletic, Laer, Dorothee von, Rolf Bjerkvig, Giroglou, Tsanan, Tsinkalovsky, Oleg, Huszthy Peter C., Skaftnesmo Kai Ove, Bjerkvig Rolf, Philipp Euskirchen, Bjerkvig, Rolf   +23 more
core   +2 more sources

A National Consensus Survey for Current Practice in Brain Tumor Management I: Antiepileptic Drug and Steroid Usage [PDF]

, 2020
Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey for diverse queries faced in the treatment of brain tumors. As part I of the survey, the aim of this study is to evaluate
김세훈, 윤홍인, 장종희
core   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Programmed cell death disrupts inflammatory tumor microenvironment (TME) and promotes glioblastoma evolution

Cell Communication and Signaling
Glioblastoma (GBM) is the most common malignant brain tumor and has a dismal prognosis even under the current first-line treatment, with a 5-year survival rate less than 7%.
Tingyu Liang, Lingui Gu, Xiaoman Kang, Junlin Li, Yixuan Song, Yu Wang, Wenbin Ma   +6 more
doaj   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

The combination of temozolomide and perifosine synergistically inhibit glioblastoma by impeding DNA repair and inducing apoptosis

Cell Death Discovery
Temozolomide (TMZ) is widely utilized as the primary chemotherapeutic intervention for glioblastoma. However, the clinical use of TMZ is limited by its various side effects and resistance to chemotherapy.
Wenpeng Zhao, Liwei Zhou, Wentao Zhao, Huiying Yang, Zhenwei Lu, Liang Zhang, Yaya Zhang, Yuanyuan Xie, Hanwen Lu, Wanhong Han, Jiawei He, Xiansheng Qiu, Fang Jia, Wujie Zhao, Bingchang Zhang, Zhanxiang Wang   +15 more
doaj   +1 more source

USP25 deubiquitinates cytosolic METTL3 to impede glioma proliferation via an m6A-independent pathway

iScience
Summary: METTL3 exhibits distinct tumorigenic roles in the nucleus and cytoplasm, but whether its post-transcriptional modifications vary by subcellular localization remains unclear.
Bingchang Zhang, Wanhong Han, Xin Gao, Wenhua Li, Jianhua Yu, Wujie Zhao, Jiawei He, Xiansheng Qiu, Zhenwei Lu, Liwei Zhou, Yahui Hu, Yuanyuan Xie, Yanyan Geng, Hanwen Lu, Wentao Zhao, Xinwen Liao, Shouren Chen, Xiyao Liu, Sifang Chen, Guowei Tan, Yaya Zhang, Zhanxiang Wang   +21 more
doaj   +1 more source

Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas

Nature Communications, 2023
Temozolomide (TMZ) is a standard treatment for glioblastoma (GBM) patients. However, TMZ has moderate therapeutic effects due to chemoresistance of GBM cells through less clarified mechanisms.
Jianxing Yin, Xiefeng Wang, Xin Ge, Fangshu Ding, Zhumei Shi, Zehe Ge, Guang Huang, Ningwei Zhao, Dongyin Chen, Junxia Zhang, Sameer Agnihotri, Yuandong Cao, Jing Ji, Fan Lin, Qianghu Wang, Qigang Zhou, Xiuxing Wang, Yongping You, Zhimin Lu, Xu Qian   +19 more
doaj   +1 more source