Results 31 to 40 of about 361,954 (339)

Brainstem atrophy in focal epilepsy destabilizes brainstem-brain interactions: Preliminary findings. [PDF]

, 2019
BACKGROUND: MR Imaging has shown atrophy in brainstem regions that were linked to autonomic dysfunction in epilepsy patients. The brainstem projects to and modulates the activation state of several wide-spread cortical/subcortical regions.
Bateman, Lisa M., Goldman, Alica M., Laxer, Kenneth D., Mueller, Susanne G., Nei, Maromi   +4 more
core   +1 more source

Sub-cortical and brainstem sites associated with chemo-stimulated increases in ventilation in humans [PDF]

, 2010
We investigated the neural basis for spontaneous chemo-stimulated increases in ventilation in awake, healthy humans. Blood oxygen level dependent (BOLD) functional MRI was performed in nine healthy subjects using T2weighted echo planar imaging.
Ackland, Akopyan, Banzett, Bertrand, Bianchi, Brannan, Cavanna, Cechetto, Chamberlin, Chamberlin, Chen, Colebatch, Corfield, Corfield, Critchley, Dick, Douglas, Douglas, Douglas R. Corfield, Duvernoy, Duvernoy, Evans, Evans, Fink, Fink, Friston, Friston, Gandevia, Gaytan, Gray, Haines, Harper, Herbert, Heywood, Hugo D. Critchley, Isaev, Kevin Murphy, Kjaer, Koos, Kubin, Kumar, Lavezzi, Leanne C. McKay, Macey, McKay, McKay, McKay, Middleton, Mink, Nathan, Pattinson, Peiffer, Plum, Plum, Ramsay, Richard S.J. Frackowiak, Schmahmann, Schwarzacher, Severinghaus, Shea, Skatrud, Smith, Smith, Talairach, Wenninger, Worsley, Xu, Yokota   +67 more
core   +2 more sources

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo, Kilian Hett, Amy Cooper, Amy E. Brown, Jessica Iregui, Manus J. Donahue, M. Erik Landman, Italo Biaggioni, Margaret Bradbury, Cynthia Wong, David Stamler, Daniel O. Claassen   +11 more
wiley   +1 more source

Brainstem Glioma in Adults [PDF]

Frontiers in Oncology, 2016
Brainstem gliomas are not nearly as common in adults as they are in children. They are likely the final common consequence not of a single disease process but of several. They can be difficult to diagnose, and are challenging to treat. Clinical studies of this diagnosis are few and generally small.
Jethro Hu, Stephen Western, Santosh Kesari   +2 more
openaire   +3 more sources

Brainstem auditory evoked responses in an equine patient population. Part II: foals. [PDF]

, 2014
BackgroundReports of the use of brainstem auditory evoked response (BAER) as a diagnostic modality in foals have been limited.Hypothesis/objectivesTo describe BAER findings and associated causes of hearing loss in foals.AnimalsStudy group 18 foals (15 ...
Aleman, M, Holliday, TA, Madigan, JE, Williams, DC   +3 more
core   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas.

Neuro-Oncology, 2019
BACKGROUND Progress in extending the survival of glioblastoma (GBM) patients has been slow. A better understanding of why patient survival remains poor is critical to developing new strategies. Postmortem studies on GBM can shed light on why patients are
M. Drumm, Karan S Dixit, S. Grimm, P. Kumthekar, R. Lukas, J. Raizer, R. Stupp, M. Chheda, Kwok-ling Kam, Matthew McCord, S. Sachdev, T. Kruser, Alicia Steffens, R. Javier, Kathleen McCortney, C. Horbinski   +15 more
semanticscholar   +1 more source

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source

Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen   +14 more
wiley   +1 more source