Results 201 to 210 of about 80,558 (315)

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Symbolic Regression‐Guided Feature Engineering for Predicting Magnetization in Cu‐Based Alloys Under Data‐Scarce Conditions

open access: yesMaterials Genome Engineering Advances, EarlyView.
A symbolic regression approach (SISSO) with physics‐informed feature engineering achieves high‐accuracy prediction of magnetic properties in Cu‐based alloys under data‐scarce conditions. The framework offers an interpretable and transferable strategy for accelerated alloy design.
Buyang Ma   +6 more
wiley   +1 more source

Robust Position Control of an Electro‐Hydraulic Actuator via Metaheuristic Optimization of a Fractional‐Order PID Controller

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT In this study, a robust position control strategy is presented for a two‐stage electro‐hydraulic actuator system using a fractional‐order proportional–integral–derivative (FOPID) controller tuned by Kirchhoff's law algorithm (KLA). Electro‐hydraulic systems exhibit strong nonlinearities, parameter uncertainties, and external disturbances ...
Ridvan Firat Cinar   +8 more
wiley   +1 more source

Design, Analysis, and Experimental Validation of a Variable‐Gap Magnetorheological Damper for Seat Suspension

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT To address the dual challenges of routine driving vibration and impact loads in vehicle seat suspensions, a novel variable‐gap magnetorheological damper (VGMRD) is proposed. By combining a tapered piston with a conformal variable‐diameter cylinder, stroke‐dependent, dual‐mode damping characteristics are achieved without the need for complex ...
Min Wei   +4 more
wiley   +1 more source

Experimental evaluation of a cost-effective tesla turbine for waste air energy recovery in transportation systems. [PDF]

open access: yesSci Rep
Farghaly MB   +5 more
europepmc   +1 more source

Detecting Loosening of Bolt‐Flanged Pipe Using Smoothed Pseudo Wigner–Ville Distribution: Digital Twin‐Based Approach Using Convolution Neural Networks

open access: yesInternational Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT In this paper, an integrated digital twin‐based fault‐diagnosis framework is proposed to detect bolt loosening in flanged pipe connections. The approach combines finite element‐based numerical modeling, experimental modal analysis, and advanced signal processing‐assisted deep learning to achieve reliable loosening detection under operational ...
Milad Shabani Yousefabad   +4 more
wiley   +1 more source

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