Results 91 to 100 of about 159,311 (302)
Advanced Science, EarlyView.We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun +13 more
wiley +1 more source
Study on the Pressure Regulation Method of New Automatic Pressure Regulating Valve in the Electronically Controlled Pneumatic Brake Systems in Commercial Vehicles. [PDF]
Sensors (Basel), 2022 Li G, Wei X, Wang Z, Bao H.
europepmc +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
STABILITY ANALYSIS OF DISC BRAKE SYSTEMS WITH UNCERTAINTY PARAMETERS
Jixie qiangdu, 2017 To suppress the brake noise of automotive disc brake systems,a stability analysis method of disc brake systems with random and fuzzy parameters was proposed.
HUANG Ya, YU DeJie, LV Hui, PENG Long
doaj
Wheel movement during braking [PDF]
, 2002 YesAn experimental study of wheel movement arising from compliance in the front suspension and steering system of a passenger car during braking is presented.
Day, Andrew J., Klaps, J.
core
Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems
Advanced Science, EarlyView.A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller +9 more
wiley +1 more source
A Hybrid Model for Freight Train Air Brake Condition Monitoring
Applied SciencesThe Digital Freight Train is expected to revolutionise the rail freight industry. A critical aspect of this transformation is real-time condition monitoring of air brake systems, which are among the leading causes of train malfunctions.
Alessandro Galimberti +2 more
doaj +1 more source
Advanced Science, EarlyView.Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan +15 more
wiley +1 more source
Dynamics of a brake system governed by modified Burridge-Knopoff-Pad model
HeliyonDespite widespread investigations to improve on the performance of automobile brake systems, the undesirable phenomenon of disc brake squeal noise remains a very challenging problem to solve. Consequently, we thus propose a basic theoretical brake system
Oma Nfor Nkeh +3 more
doaj +1 more source
Periodically Controlled Hybrid Systems: Verifying A Controller for An Autonomous Vehicle [PDF]
, 2008 This paper introduces Periodically Controlled Hybrid Automata (PCHA) for describing a class of hybrid control systems. In a PCHA, control actions occur roughly periodically while internal and input actions, may occur in the interim changing the discrete ...
, +4 more
core +2 more sources