Results 71 to 80 of about 159,311 (302)

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

High-Transparency Linear Actuator Using an Electromagnetic Brake for Damping Modulation in Physical Human–Robot Interaction

Journal of Sensor and Actuator Networks
Enhancing the transparency of high-transmission-ratio linear actuators is crucial for improving the safety and capability of high-force robotic systems having physical contact with humans in unstructured environments.
Zahid Ullah, Thachapan Sermsrisuwan, Khemwutta Pornpipatsakul, Ronnapee Chaichaowarat, Witaya Wannasuphoprasit   +4 more
doaj   +1 more source

Brake tests to evaluate the human behaviour at different brake pedal characteristics [PDF]

-Brake-by-wire represents the replacement of traditional brake components such as pumps, hoses, fluids, brake boosters, and tandem master cylinders by electronic sensors and actuators.
Ball, Andrew, Mishra, Rakesh, Retzer, Hermann, Schmidt, Karsten, Stephenson, John   +4 more
core  

Integral high order sliding mode control of a brake system [PDF]

, 2013
The aim of this paper is to present the design of a robust sliding mode control scheme for a vehicle system which consists of active brake systems. The proposed control strategy is based on the combination of high order sliding mode control methods and ...
Loukianov, Alexander, Navarrete-Guzmán, Antonio, Sánchez-Torres, Juan D.   +2 more
core  

DPN -- Dependability Priority Numbers

, 2020
This paper proposes a novel model-based approach to combine the quantitative dependability (safety, reliability, availability, maintainability and IT security) analysis and trade-off analysis.
Guo, Zhensheng, Zeller, Marc
core   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Reactive Braking System

International Journal of Engineering & Technology, 2018
This paper is based on the simplifying technique of the existing technology called Autonomous Emergency Braking (AEB) by using a simple electronic setup which can be easily installed in all the existing four-wheelers without changing its existing working system.
Nagendran N, Rani K S, Punitha P, Vaishnav V P, Balaji V, Na.nagendran@gmail.com S   +5 more
openaire   +2 more sources

The MOD-OA 200 kilowatt wind turbine generator design and analysis report [PDF]

The project requirements, approach, system description, design requirements, design, analysis, system tests, installation safety considerations, failure modes and effects analysis, data acquisition, and initial performance for the MOD-OA 200 kw wind ...
Andersen, T. S., Bodenschatz, C. A., Eggers, A. G., Hughes, P. S., Lampe, R. F., Lipner, M. H., Schornhorst, J. R.   +6 more
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source