Results 101 to 110 of about 24,756,041 (332)
STABILITY ANALYSIS OF DISC BRAKE SYSTEMS WITH UNCERTAINTY PARAMETERS
Jixie qiangdu, 2017 To suppress the brake noise of automotive disc brake systems,a stability analysis method of disc brake systems with random and fuzzy parameters was proposed.
HUANG Ya, YU DeJie, LV Hui, PENG Long
doaj
PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Advanced Science, EarlyView.Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu +11 more
wiley +1 more source
A Hybrid Model for Freight Train Air Brake Condition Monitoring
Applied SciencesThe Digital Freight Train is expected to revolutionise the rail freight industry. A critical aspect of this transformation is real-time condition monitoring of air brake systems, which are among the leading causes of train malfunctions.
Alessandro Galimberti +2 more
doaj +1 more source
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
The design of aircraft brake systems, employing cooling to increase brake life [PDF]
A research program was initiated to determine the feasibility of using cooling to increase brake life. An air cooling scheme was proposed, constructed and tested with various designs. Straight and curved slotting of the friction material was tested.
Ho, T. L. +2 more
core +1 more source
Dynamics of a brake system governed by modified Burridge-Knopoff-Pad model
HeliyonDespite widespread investigations to improve on the performance of automobile brake systems, the undesirable phenomenon of disc brake squeal noise remains a very challenging problem to solve. Consequently, we thus propose a basic theoretical brake system
Oma Nfor Nkeh +3 more
doaj +1 more source
, 2007 The dynamics of brake systems is determined by the growth and destruction of characteristic hard, smooth and friction-intensive structures (“patches”) on brake pads.
M. Müller, G. Ostermeyer
semanticscholar +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Review of antiskid and brake dynamics research [PDF]
, 1981 The behavior of various antiskid systems was investigated under controlled conditions. Results from utilizing a single main wheel of a DC-9 aircraft suggest that the systems investigated perform well under most circumstances but there may be room for ...
Stubbs, S. M., Tanner, J. A.
core +1 more source
Advanced Science, EarlyView.Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao +3 more
wiley +1 more source