Results 61 to 70 of about 76,469 (342)

Segmenting wine markets with diverse price functions: Evidence from California red and white wines sold in British Columbia

Wine Economics and Policy, 2017
Previous hedonic price studies on wine market segments, exploring diverse price functions, are constrained by pre-determined price breakpoints, the total number of segments, or both.
Richard Carew, Wojciech J. Florkowski, Ting Meng   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Assessing the economic burden and health-related quality of life in chinese patients with fibrodysplasia ossificans progressiva: a questionnaire survey analysis

Orphanet Journal of Rare Diseases
Background Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare, disabling genetic disorder condition that lacks real-world evidence on disease burden.
Xiaoyang Xu, Xiaoning He, Wei Wu, Yuhang Xin, Qingnan Li, Lei Song, Kexin Li, Jing Wu   +7 more
doaj   +1 more source

A branch-and-price algorithm for the Minimum Latency Problem

Computers & Operations Research, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Teobaldo Bulhões, Ruslan Sadykov, Eduardo Uchoa   +2 more
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Quantum Subroutines in Branch-Price-and-Cut for Vehicle Routing

IEEE Transactions on Quantum Engineering
Motivated by recent progress in quantum hardware and algorithms, researchers have developed quantum heuristics for optimization problems, aiming for advantages over classical methods.
Friedrich Wagner, Frauke Liers
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

FI-CAECNet: A Frequency-Aware IMF-Wise Closed-Loop Adaptive Error Correction Network for Stock Price Forecasting

IEEE Access
Stock price forecasting remains challenging because financial time series usually exhibit nonstationarity, strong noise, nonlinear dynamics, multi-scale fluctuations, and abrupt short-term shocks.
Gaofeng Liu
doaj   +1 more source

ANALISIS PENGARUH BAURAN PEMASARAN TERHADAP PENGAMBILAN KEPUTUSAN MENABUNG BRITAMA PADA PT BANK RAKYAT INDONESIA (PERSERO), Tbk CABANG PEMBANTU PURI ANJASMORO SEMARANG

Keunis, 2019
This study aims to determine the significance of marketing mix variables consisting of product, price, promotion, place, people, processe, and physical evidence of BritAma saving decision making at PT Bank Rakyat Indonesia (Persero), Branch of Puri ...
Kinanda Nor Cahya Ningtias, Embun Duriany Soemarso   +1 more
doaj   +1 more source