Results 51 to 60 of about 941,906 (303)

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

open access: yesAdvanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu   +7 more
wiley   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

Praktik Murabahah pada Perbankan Syariah di Kendari

open access: yesAl-Ulum, 2017
This study aims to determine the murabahah financing practices in Islamic banking with a case study in Kendari Branch BMI. This research employs the qualitative research and descriptive explorative research by implementing interview technique ...
Ummi Kalsum
doaj   +1 more source

The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells

open access: yesAdvanced Science, EarlyView.
Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato   +9 more
wiley   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

open access: yesAdvanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang   +8 more
wiley   +1 more source

Faktor-Faktor Yang Mempengaruhi Niat Adopsi Mobile Banking Bank Syariah Indonesia di Kabupaten Kudus

open access: yesAl-Intaj
This article describes the results of testing the theory of planned behavior (TPB) which specifically examines the factors influencing intention of adoption of mobile banking.
Fatikha Rizqya Nur   +2 more
doaj   +1 more source

Branch Banking, Bank Competition, and Financial Stability [PDF]

open access: yes
It is often argued that branching stabilizes banking systems by facilitating diversification of bank portfolios; however, previous empirical research on the Great Depression offers mixed support for this view.
Mark Carlson, Kris James Mitchener
core  

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

open access: yesAdvanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi   +11 more
wiley   +1 more source

Ranking of Financial Technology Indicators of Banks based on Fuzzy Approach [PDF]

open access: yesراهبرد مدیریت مالی
In the current era, it was created using technology, on one hand, financial institutions and banks did not accept this trend, on the other hand, in the country, there has been an evaluation of the performance of certain banking institutions and ...
Reza Tehrani   +2 more
doaj   +1 more source

The case for interstate branch banking [PDF]

open access: yes
During the 1980’s, many states relaxed laws restricting branching, and most states opened up their borders to entry by out-of-state bank holding companies. This article suggests that both banks and consumers would benefit if laws were further modified to
David L. Mengle
core  

Home - About - Disclaimer - Privacy