Results 81 to 90 of about 107,665 (309)

Oxidative Synthesis of Benzo[1,4]oxazines from α-Branched Primary Amines and Ortho-Benzoquinones

, 2019
The efficient oxidative construction of benzo[1,4]oxazines from simple α-branched amines and ortho-benzoquinones is reported. The procedure pivots on a triethylamine and iodine mediated oxidative ring closure from the ketimine intermediate formed upon ...
Darren J., Dixon, Jamie, Leitch, Dhananjayan, Vasu   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Isolation and purification of DNA double-strand break repair intermediates for understanding complex molecular mechanisms.

PLoS ONE
Branched DNA molecules are key intermediates in the molecular pathways of DNA replication, repair and recombination. Understanding their structural details, therefore, helps to envisage the mechanisms underlying these processes.
Tahirah Yasmin, Benura Azeroglu, Fares Osam Yanez-Cuna, Sally Jones, Patrick Yizhi Cai, David R F Leach   +5 more
doaj   +1 more source

Branched affine and projective structures on compact Riemann surfaces

, 1988
It is first established that there exist linear manifolds of branched affine structures having certain nonpolar branch divisors and simple polar divisors on an arbitrary compact Riemann surface M of genus g≤1.
Masterson, John T.
core   +1 more source

Connectivity results for surface branched ideal triangulations [PDF]

, 2020
We consider triangulations of closed surfaces S with a given set of vertices V; every triangulation can be branched that is en-hanced to be a [increment]-complex. Branched triangulations are considered up to the b-transit equivalence generated by b-flips
Benedetti, Riccardo, Benedetti R.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optical branched flow in nonlocal nonlinear medium

Nanophotonics
When light propagates through a randomly correlated, slowly varying medium, it generates optical branched flow. Previous studies have demonstrated that the self-focusing effect in optical media can accelerate the appearance of the first branching points ...
Zhao Tongxun, Wang Yudian, Peng Ruihan, Wang Peng, Ye Fangwei   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Modular frobenius manifolds and their invariant flows [PDF]

, 2010
The space of Frobenius manifolds has a natural involutive symmetry on it: there exists a map I which sends a Frobenius manifold to another Frobenius manifold.
I. A. B. Strachan, Morrison, E.K., E. K. Morrison, Strachan, I.   +3 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source