Results 61 to 70 of about 696,423 (315)
The Library of Parliament’s Competency-Based New-Librarian Development Program
Partnership: The Canadian Journal of Library and Information Practice and Research, 2023 Employee orientation and development are essential organizational processes. This paper examines a competency-based new-librarian development program in a legislative library setting, emphasizing program redesign and continuous improvement.
Melissa Fraser-Arnott, Maureen Martyn
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BRANCHES OF THE ASSOCIATION. [PDF]
Journal of the American Medical Association, 1886 To the Editor of the Journal: Dear Sir: —I have carefully read the letters which have followed the appearance of "Branch's" communication, and am rather surprised at the position which some of your correspondents have taken. In his last letter (Journalof March 6) "Branch" states that his object is "to increase the influence of the Association, and ...
openaire +4 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Energy Consumption during Cutting Tree Branches of Fig (Ficus carica) [PDF]
Journal of Soil Sciences and Agricultural Engineering, 2019 This study evaluated energy consumption for cutting tree branches of the fig in different moisture contents (MC) levels at 10, 16, 20 and 25 % w.b., branch diameter levels at 0.5, 1, 1.5 and 2 cm, two types of cutting knives, smooth & serrated and ...
علاء عونى, أحمد الشال
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Acute generalized exanthematous pustulosis: A retrospective study of 51 cases in Taiwan
Dermatologica Sinica, 2014 Background/Objective: Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction characterized by fever and numerous sterile non-follicular pustules.
Yung-Yi Lee, Wen-Hung Chung
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FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source