Results 61 to 70 of about 815,658 (304)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Missing Women and Bare Branches: Gender Balance and Conflict [PDF]
, 2005 The emerging subfield of “security demographics” examines the linkages between population dynamics and the security trajectories of nation-states.
Hudson, Valerie M, den Boer, Andrea
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
The impact of switching costs on closing of service branches [PDF]
The paper deals with the optimal location of service branches. Consumers can receive service from different firms and branches offering substitute services. The consumer chooses the firm and the branch.
Baron, Mira G.
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Acute generalized exanthematous pustulosis: A retrospective study of 51 cases in Taiwan
Dermatologica Sinica, 2014 Background/Objective: Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction characterized by fever and numerous sterile non-follicular pustules.
Yung-Yi Lee, Wen-Hung Chung
doaj +1 more source
Physical Review Letters, 2012 We propose a method for quantization of Lagrangians for which the Hamiltonian, as a function of momentum, is a branched function with cusps. Appropriate boundary conditions, which we identify, insure unitary time evolution. In special cases a dual (canonical) transformation maps the problem into a problem of quantum mechanics on singular spatial ...
Shapere, Alfred, Wilczek, Frank
openaire +6 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Leśne Prace Badawcze, 2019 The frequency and diversity of fungi in branches, roots and soil was examined in 3–10-years-old diseased Juniperus x media trees growing in the surroundings of the sewage treatment facility in Poznań.
Behnke-Borowczyk Jolanta +3 more
doaj +1 more source