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Cytoskeleton and Membrane Organization at Axon Branches
Axon branching is a critical process ensuring a high degree of interconnectivity for neural network formation. As branching occurs at sites distant from the soma, it is necessary that axons have a local system to dynamically control and regulate axonal ...
Satish Bodakuntla+4 more
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Asymptotic genealogy of a critical branching process
Consider a continuous-time binary branching process conditioned to have population size n at some time t, and with a chance p for recording each extinct individual in the process.
Popovic, Lea
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This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke+12 more
wiley +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
This paper is concerned with a simple mathematical model for a branching stochastic process. Using the language of family trees we may illustrate the process as follows. The probability that a man has exactly $r$ sons is $p_r, r = 0, 1, 2, \cdots$. Each of his sons (who together make up the first generation) has the same probabilities of having a given
openaire +2 more sources
Stochastic two-group models with transmission dependent on host infectivity or susceptibility
Stochastic epidemic models with two groups are formulated and applied to emerging and re-emerging infectious diseases. In recent emerging diseases, disease spread has been attributed to superspreaders, highly infectious individuals that infect a large ...
Aadrita Nandi, Linda J. S. Allen
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Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Limit theorems for continuous time branching flows [PDF]
We construct a flow of continuous time and discrete state branching processes. Some scaling limit theorems for the flow are proved, which lead to the path-valued branching processes and nonlocal branching superprocesses over the positive half line studied in Li (2012).
arxiv
Branching processes for the fragmentation equation [PDF]
We investigate branching properties of the solution of a stochastic differential equation of fragmentation (SDEF) and we properly associate a continuous time càdlàg Markov process on the space S# of all fragmentation sizes, introduced by J. Bertoin. A binary fragmentation kernel induces a specific class of integral type branching kernels and taking as ...
Madalina Deaconu+6 more
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Branching Process in a Stochastic Extremal Model
We considered a stochastic version of the Bak-Sneppen model (SBSM) of ecological evolution where the the number $M$ of sites mutated in a mutation event is restricted to only two. Here the mutation zone consists of only one site and this site is randomly
Manna, S. S.
core +1 more source