Results 91 to 100 of about 913,345 (341)

Cytoskeleton and Membrane Organization at Axon Branches

open access: yesFrontiers in Cell and Developmental Biology, 2021
Axon branching is a critical process ensuring a high degree of interconnectivity for neural network formation. As branching occurs at sites distant from the soma, it is necessary that axons have a local system to dynamically control and regulate axonal ...
Satish Bodakuntla   +4 more
doaj   +1 more source

Asymptotic genealogy of a critical branching process

open access: yes, 2005
Consider a continuous-time binary branching process conditioned to have population size n at some time t, and with a chance p for recording each extinct individual in the process.
Popovic, Lea
core   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Branching Processes

open access: yesThe Annals of Mathematical Statistics, 1948
This paper is concerned with a simple mathematical model for a branching stochastic process. Using the language of family trees we may illustrate the process as follows. The probability that a man has exactly $r$ sons is $p_r, r = 0, 1, 2, \cdots$. Each of his sons (who together make up the first generation) has the same probabilities of having a given
openaire   +2 more sources

Stochastic two-group models with transmission dependent on host infectivity or susceptibility

open access: yesJournal of Biological Dynamics, 2019
Stochastic epidemic models with two groups are formulated and applied to emerging and re-emerging infectious diseases. In recent emerging diseases, disease spread has been attributed to superspreaders, highly infectious individuals that infect a large ...
Aadrita Nandi, Linda J. S. Allen
doaj   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Limit theorems for continuous time branching flows [PDF]

open access: yesarXiv, 2012
We construct a flow of continuous time and discrete state branching processes. Some scaling limit theorems for the flow are proved, which lead to the path-valued branching processes and nonlocal branching superprocesses over the positive half line studied in Li (2012).
arxiv  

Branching processes for the fragmentation equation [PDF]

open access: yesStochastic Processes and their Applications, 2015
We investigate branching properties of the solution of a stochastic differential equation of fragmentation (SDEF) and we properly associate a continuous time càdlàg Markov process on the space S# of all fragmentation sizes, introduced by J. Bertoin. A binary fragmentation kernel induces a specific class of integral type branching kernels and taking as ...
Madalina Deaconu   +6 more
openaire   +3 more sources

Branching Process in a Stochastic Extremal Model

open access: yes, 2009
We considered a stochastic version of the Bak-Sneppen model (SBSM) of ecological evolution where the the number $M$ of sites mutated in a mutation event is restricted to only two. Here the mutation zone consists of only one site and this site is randomly
Manna, S. S.
core   +1 more source

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