Results 71 to 80 of about 10,767,248 (303)

On Minkowskian Branching Structures [PDF]

open access: yes, 2006
We introduce the notion of a Minkowskian Branching Structure ("MBS" for short). Then we prove some results concerning the phenomenon of funny business in its finitary and infinitary ...
Placek, Tomasz, Wronski, Leszek
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Stochastic two-group models with transmission dependent on host infectivity or susceptibility

open access: yesJournal of Biological Dynamics, 2019
Stochastic epidemic models with two groups are formulated and applied to emerging and re-emerging infectious diseases. In recent emerging diseases, disease spread has been attributed to superspreaders, highly infectious individuals that infect a large ...
Aadrita Nandi, Linda J. S. Allen
doaj   +1 more source

Branching processes in random environment [PDF]

open access: yes, 2011
In der folgenden Arbeit werden Eigenschaften von Verzweigungsprozessen in zufälliger Umgebung (engl. branching processes in random environment, kurz BPREs) untersucht. Das Modell geht auf Smith (1969) und Athreya (1971) zurück. Ein BPRE ist ein einfaches
Böinghoff, Christian
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Turing mechanism underlying a branching model for lung morphogenesis. [PDF]

open access: yesPLoS ONE, 2017
The mammalian lung develops through branching morphogenesis. Two primary forms of branching, which occur in order, in the lung have been identified: tip bifurcation and side branching.
Hui Xu, Mingzhu Sun, Xin Zhao
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Funny business in branching space-times: Infinite modal correlations [PDF]

open access: yes, 2006
The theory of branching space-times is designed as a rigorous framework for modelling indeterminism in a relativistically sound way. In that framework there is room for ``funny business'', i.e., modal correlations such as occur through quantum-mechanical
Belnap, Nuel   +2 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Discovering branching conditions from business process execution logs

open access: yes, 2013
Process mining is a family of techniques to discover business process models and other knowledge of business processes from event logs. Existing process mining techniques are geared towards discovering models that capture the order of execution of tasks,
Leoni, de, M.   +4 more
core   +1 more source

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