Results 61 to 70 of about 159,216 (306)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Branching processes in random environment [PDF]

open access: yes, 2011
In der folgenden Arbeit werden Eigenschaften von Verzweigungsprozessen in zufälliger Umgebung (engl. branching processes in random environment, kurz BPREs) untersucht. Das Modell geht auf Smith (1969) und Athreya (1971) zurück. Ein BPRE ist ein einfaches
Böinghoff, Christian
core  

Branching bisimilarity with explicit divergence [PDF]

open access: yes, 2009
We consider the relational characterisation of branching bisimilarity with explicit divergence. We prove that it is an equivalence and that it coincides with the original definition of branching bisimilarity with explicit divergence in terms of coloured ...
Glabbeek, van, R.J.   +5 more
core   +1 more source

Stochastic hypothesis of transition from inborn neutropenia to AML: Interactions of cell population dynamics and population genetics

open access: yesFrontiers in Oncology, 2013
We present a stochastic model of driver mutations in the transition from severe congenital neutropenia to myelodysplastic syndrome to acute myeloid leukemia (AML). The model has the form of a multitype branching process.
Marek eKimmel, Seth eCorey
doaj   +1 more source

Bim Expression Modulates Branching Morphogenesis of the Epithelium and Endothelium

open access: yesBiomolecules, 2022
Branching morphogenesis is a key developmental process during organogenesis, such that its disruption frequently leads to long-term consequences.
Christine M. Sorenson   +6 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Stochastic two-group models with transmission dependent on host infectivity or susceptibility

open access: yesJournal of Biological Dynamics, 2019
Stochastic epidemic models with two groups are formulated and applied to emerging and re-emerging infectious diseases. In recent emerging diseases, disease spread has been attributed to superspreaders, highly infectious individuals that infect a large ...
Aadrita Nandi, Linda J. S. Allen
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

TAPAs: A Tool for the Analysis of Process Algebras [PDF]

open access: yes, 2008
Process algebras are formalisms for modelling concurrent systems that permit mathematical reasoning with respect to a set of desired properties. TAPAs is a tool that can be used to support the use of process algebras to specify and analyze concurrent ...
Calzolai, Francesco   +11 more
core   +1 more source

Turing mechanism underlying a branching model for lung morphogenesis. [PDF]

open access: yesPLoS ONE, 2017
The mammalian lung develops through branching morphogenesis. Two primary forms of branching, which occur in order, in the lung have been identified: tip bifurcation and side branching.
Hui Xu, Mingzhu Sun, Xin Zhao
doaj   +1 more source

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