Results 61 to 70 of about 159,160 (305)

A multi-host deterministic-stochastic framework for giardiasis transmission: branching-process extinction analysis and continuous-time Markov chain dynamics

open access: yesFrontiers in Applied Mathematics and Statistics
Giardiasis remains a widespread waterborne disease with substantial public health importance, particularly in settings with inadequate sanitation and high environmental contamination.
Christopher Chukwuma Asogwa   +3 more
doaj   +1 more source

Stochastic two-group models with transmission dependent on host infectivity or susceptibility

open access: yesJournal of Biological Dynamics, 2019
Stochastic epidemic models with two groups are formulated and applied to emerging and re-emerging infectious diseases. In recent emerging diseases, disease spread has been attributed to superspreaders, highly infectious individuals that infect a large ...
Aadrita Nandi, Linda J. S. Allen
doaj   +1 more source

Bim Expression Modulates Branching Morphogenesis of the Epithelium and Endothelium

open access: yesBiomolecules, 2022
Branching morphogenesis is a key developmental process during organogenesis, such that its disruption frequently leads to long-term consequences.
Christine M. Sorenson   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Turing mechanism underlying a branching model for lung morphogenesis. [PDF]

open access: yesPLoS ONE, 2017
The mammalian lung develops through branching morphogenesis. Two primary forms of branching, which occur in order, in the lung have been identified: tip bifurcation and side branching.
Hui Xu, Mingzhu Sun, Xin Zhao
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Non-Elementary Complexities for Branching VASS, MELL, and Extensions

open access: yes, 2014
We study the complexity of reachability problems on branching extensions of vector addition systems, which allows us to derive new non-elementary complexity bounds for fragments and variants of propositional linear logic.
Ranko Lazic   +3 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Efficient qualitative analysis of classes of recursive markov decision processes and simple stochastic games [PDF]

open access: yes, 2006
. Recursive Markov Decision Processes (RMDPs) and Recursive Simple Stochastic Games (RSSGs) are natural models for recursive systems involving both probabilistic and non-probabilistic actions.
Mihalis Yannakakis   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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