Results 101 to 110 of about 125,620 (311)
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Convergence Rates and Limit Theorems for the Dual Markov Branching Process
This paper studies aspects of the Siegmund dual of the Markov branching process. The principal results are optimal convergence rates of its transition function and limit theorems in the case that it is not positive recurrent.
Anthony G. Pakes
doaj +1 more source
Functional Limit Theorems for Occupation Time Fluctuations of Branching Systems in the Case of Long-Range Dependence [PDF]
Functional central limit theorem; Occupation time uctuation; Branching particle system; Distribution-valued Gaussian process; Fractional Brownian motion; Sub-fractional Brownian motion; Long-range ...
Luis G. Gorostiza +2 more
core
Diffusion processes and coalescent trees [PDF]
We dedicate this paper to Sir John Kingman on his 70th Birthday. In modern mathematical population genetics the ancestral history of a population of genes back in time is described by John Kingman’s coalescent tree.
R. C. Griffiths +7 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Electrostatics on branching processes
We study systems of repelling particles living on the boundary of a Galton–Watson branching process. The profinite completion of such a tree carries a natural ultrametric determined by the branching structure, and the interaction energy of a pair of particles is taken to be minus the logarithm of this ultrametric distance.
openaire +2 more sources
3D modelling of branching in plants
Shoot branching is a key determinant of overall aboveground plant form. During plant development, the number of branches formed strongly influences the amount of light absorbed by the plant, and thus the plant’s competitive strength in terms of light ...
Evers, J.B.
core
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Asymptotic behaviour of estimators of the parameters of nearly unstable INAR(1) models
A sequence of first-order integer-valued autoregressive type (INAR(1)) processes is investigated, where the autoregressive type coefficients converge to 1.
Martien C. A. van Zuijlen +5 more
core +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

