Results 81 to 90 of about 112,343 (263)

APPROXIMATE FILTER FOR JUMP-DIFFUSION MODELS

open access: yesНаучный вестник МГТУ ГА, 2016
A new approach to the optimal filtering problem for jump-diffusion models is considered in this paper. This approach is based on the statistical modeling method (Monte Carlo method).
K. A. Rybakov
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Electrostatics on branching processes

open access: yesJournal of Mathematical Physics
We study systems of repelling particles living on the boundary of a Galton–Watson branching process. The profinite completion of such a tree carries a natural ultrametric determined by the branching structure, and the interaction energy of a pair of particles is taken to be minus the logarithm of this ultrametric distance.
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Tree‐ensemble analysis assesses presence of multifurcations in single cell data

open access: yesMolecular Systems Biology, 2019
We introduce TreeTop, an algorithm for single cell data analysis to identify and assign a branching score to branch points in biological processes which may have multi‐level branching hierarchies.
Will Macnair   +3 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

The ecological basis of morphogenesis: branching patterns in swarming colonies of bacteria

open access: yesNew Journal of Physics, 2014
Understanding how large-scale shapes in tissues, organs and bacterial colonies emerge from local interactions among cells and how these shapes remain stable over time are two fundamental problems in biology. Here we investigate branching morphogenesis in
Pan Deng   +3 more
doaj   +1 more source

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