Results 71 to 80 of about 5,392,495 (304)
An investigation of cognitive 'branching' processes in major depression
BMC Psychiatry, 2009 Background Patients with depression demonstrate cognitive impairment on a wide range of cognitive tasks, particularly putative tasks of frontal lobe function.
Williams Steven CR +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On Minkowskian Branching Structures [PDF]
, 2006 We introduce the notion of a Minkowskian Branching Structure ("MBS" for short). Then we prove some results concerning the phenomenon of funny business in its finitary and infinitary ...
Placek, Tomasz, Wronski, Leszek
core
Filtering for jump-diffusion models by statistical modeling method
Научный вестник МГТУ ГА, 2016 This article develops new methods that reduce the optimal filtering problem for jump-diffusion models to the analysis problem for the special stochastic system with jumps, branching and terminating trajectories. Earlier appropriate methods and algorithms
K. A. Rybakov
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
On the Stationary Measure for Markov Branching Processes
MathematicsA previous study determined criteria ensuring that a probability distribution supported in positive integers is the limiting conditional law of a subcritical Markov branching process.
Anthony G. Pakes
doaj +1 more source
Conductivity of Random Trees and the Existence of Infinite Conducting Components- Percolation Model [PDF]
The Egyptian Statistical Journal, 1991 Let T be an infinite tree in which every vertex α has, independently of the other vertices, a random degree d(α) and every edge has, independently of the other edges, a random conductivity σ. We employ the moment generating function's technique to obtain
Boualem Bendjilali +2 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Fractal Dimensions of Random Trees [PDF]
The Egyptian Statistical Journal, 1994 Our goal in this paper is to determine whether the fractal dimensions (FD) of random trees is finite. Two types of random trees are considered. We first consider spherically symmetric random trees in which all vertices at level n have degree 3 with ...
Mokhtar Konsowa
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source