Results 31 to 40 of about 4,978,756 (344)

What Is the Molecular Signature of Mind–Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices

open access: yesFrontiers in Immunology, 2017
There is considerable evidence for the effectiveness of mind–body interventions (MBIs) in improving mental and physical health, but the molecular mechanisms of these benefits remain poorly understood.
Ivana Buric   +8 more
doaj   +1 more source

Geographic Expansion of Sporotrichosis, Brazil

open access: yesEmerging Infectious Diseases, 2020
Brazil has experienced geographic expansion of zoonotic sporotrichosis. Social problems in the country contribute substantially to the expansion. A comprehensive sporotrichosis control program is beyond the sphere of public health.
I. D. Gremião   +4 more
semanticscholar   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Issues and Challenges in Open and Distance e-Learning: Perspectives from the Philippines

open access: yesInternational Review of Research in Open and Distributed Learning, 2016
Rapid advances in information and communications technology in the digital age have brought about significant changes in the practice of distance education (DE) worldwide.
Patricia Brazil Arinto
doaj   +1 more source

IMAGENS DO FEMININO NO BANQUETE DE PLATÃO: SÓCRATES E A FLAUTISTA

open access: yesKínesis, 2021
O presente trabalho tem como objetivo central a análise e discussão da questão do feminino nos cinco primeiros discursos que compõem um dos mais célebres diálogos platônicos, O Banquete.
Vicente Thiago Freire Brazil
doaj   +1 more source

Firms, Informality, and Development: Theory and Evidence from Brazil

open access: yesThe American Economic Review, 2018
This paper develops and estimates an equilibrium model where heterogeneous firms can exploit two margins of informality: (i) not register their business, the extensive margin; and (ii) hire workers “off the books,” the intensive margin.
Gabriel Ulyssea
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A taxonomic revision of Camptocerus Dejean (Coleoptera: Curculionidae: Scolytinae) [PDF]

open access: yes, 2010
The Neotropical ambrosia beetle genus Camptocerus Dejean was revised. Monophyly of the genus was tested using 66 morphological characters in a cladistic analysis. Camptocerus was recovered as monophyletic and 31 species were recognized.
Cognato, Anthony I., Smith, Sarah M.
core   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Extreme Drought Events over Brazil from 2011 to 2019

open access: yesAtmosphere, 2019
Drought-related disasters are among the natural disasters that are able to cause large economic and social losses. In recent years, droughts have affected different regions of Brazil, impacting water, food, and energy security. In this study, we used the
A. P. Cunha   +13 more
semanticscholar   +1 more source

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