Results 31 to 40 of about 4,256,926 (340)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Pausânias no Banquete de Platão: Encômio ao Eros sofístico [Pausanias in Plato’s Symposium: encomium to Eros sophistic]

open access: yesKalagatos, 2017
O presente artigo tem como objetivo refletir sobre os fundamentos teóricos que balizam os argumentos apresentados por Pausânias em seu célebre discurso no Banquete.
Vicente Brazil
doaj  

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

DO "CONHECE-TE A TI MESMO" AO "TORNA-TE QUEM TU ÉS": NIETZSCHE CONTRA SÓCRATES EM ECCE HOMO

open access: yesRevista Trágica, 2019
A partir de uma passagem interessante da autobiografia do filósofo, trabalharemos dois imperativos gregos, o “Conhece-te a ti mesmo”, do oráculo de Delfos, e o “Torna-te o que tu és”, do poeta Píndaro.
Luciano Gomes Brazil
doaj   +1 more source

Alzheimer's disease: an epidemiological analysis over the number of hospitalizations and deaths in Brazil

open access: yesArquivos de Neuro-Psiquiatria, 2023
Background Alzheimer's disease (AD) is a neurodegenerative condition characterized by impaired cognitive function. It results in high morbidity, including a large number of hospitalizations, and mortality, generating high costs to health systems.
Eduardo Cattapan Piovesan   +3 more
doaj   +1 more source

The role of protected areas in maintaining natural vegetation in Brazil [PDF]

open access: gold, 2021
Daniel Gonçalves-Souza   +3 more
openalex   +1 more source

Hosting Mediations as a Representative of the System of Civil Justice [PDF]

open access: yes, 2007
Published in cooperation with the American Bar Association Section of Dispute ...
Brazil, Wayne D.
core  

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih   +40 more
wiley   +1 more source

The Strategic Communication Planning in an emergency at the Almirante Álvaro Alberto Nuclear Power Plant (CNAAA)

open access: yesBrazilian Journal of Radiation Sciences, 2023
In a world where information has a high speed of propagation and is present in the most diverse media, it is essential to follow the news in order to keep the population informed about the actions taken, the real risks and the consequences of an alleged ...
Fernando Barcellos Razuck   +2 more
doaj   +1 more source

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