Results 71 to 80 of about 66,848 (96)

Durable complete radiographic and biochemical response to olaparib in BRCA2-mutated metastatic castration-resistant prostate cancer: a long-term responder case. [PDF]

Urol Case Rep
Ito F, Kobayashi K, Hayashi G, Kamijo S, Fujita T.   +4 more
europepmc   +1 more source

The expanding roles of homologous recombination proteins in genome stability. [PDF]

EMBO J
Sassi L, Martinez Marroquin A, Waked S, Ardizzoia A, Costanzo V.   +4 more
europepmc   +1 more source

Germline BRCA1/2 Variants in Polish Patients with Family History of Breast and Ovarian Cancer: Prevalence, CNV Detection, and Identification of a Novel Loss-of-Function Mutation. [PDF]

Curr Oncol
Skoczylas S, Płoszaj T, Dróżdż I, Moczulska H, Serafin M, Piekarska K, Wojtyczka O, Żeżawska K, Zmysłowska A.   +8 more
europepmc   +1 more source

The Contribution of Genetic Modifiers to Ovarian Cancer Risk in <i>BRCA1</i> and <i>BRCA2</i> Pathogenic Variant Carriers. [PDF]

Cancers (Basel)
Cylwik D, Dwornik R, Białkowska K.
europepmc   +1 more source

Revisiting the impact of BRCA1 pathogenic variants on the aggressiveness of prostate cancer. [PDF]

JNCI Cancer Spectr
Sasagawa H, Narita S, Matsuda K, Kosaka T, Momozawa Y.   +4 more
europepmc   +1 more source

Drastic Response to Olaparib in a Patient With Metastatic Castration-Resistant Prostate Cancer Harboring BRCA2 Alterations and Near-Threshold Tumor Mutational Burden. [PDF]

IJU Case Rep
Yokota K, Kosaka T, Daimon T, Fujiwara S, Nakamura K, Nishihara H, Oya M.   +6 more
europepmc   +1 more source

Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality. [PDF]

Nat Commun
Milordini G, Zacco E, Masi M, Armaos A, Di Palma F, Oneto M, Gilodi M, Rupert J, Broglia L, Varignani G, Scotto M, Marotta R, Girotto S, Cavalli A, Tartaglia GG.   +14 more
europepmc   +1 more source

Germline variants in ATM, BRCA2, other cancer predisposition and novel candidate genes are implicated in glioma risk in adult glioma patients with a familial or personal history of tumors. [PDF]

Acta Neuropathol
Brand F, Rose LS, Akbarzadeh AH, Weber CAM, Eckert I, Schmidt G, Auber B, Förster A, Beyer U, Geffers R, Bartels S, Lalk M, Polemikos M, Friese M, Sabel M, Schwenkenbecher P, Kremer P, Nabavi A, Samii A, Lehmann U, Reifenberger G, Krauss JK, Wiese B, Hartmann C, Weber RG.   +24 more
europepmc   +1 more source

The Concordance of Secondary Pathogenic Germline Variants Identified by Tumor Genomic Profiling in Adult Solid Tumor Patients at Two US Community Cancer Centers. [PDF]

Genes (Basel)
Moncado S, Darabi S, Ivankovic D, Boccuto L.   +3 more
europepmc   +1 more source