Results 171 to 180 of about 20,494 (185)

Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide

Bioorganic and Medicinal Chemistry, 2020
Jinpei Zhou
exaly  

Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes

European Journal of Medicinal Chemistry, 2021
Hongchun Liu
exaly  

Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function

Circulation, 2020
Bret M Evers, Kristin M French, Francisco Altamirano   +2 more
exaly  

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

Cancer Cell, 2018
Zhenlin Ju, Jun Yin
exaly  

MYC protein stability is negatively regulated by BRD4

Proceedings of the National Academy of Sciences of the United States of America, 2020
Laura Baranello, Jie Mu, Sheetal Uppal
exaly  

Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

Molecular Cell, 2017
Ivan Đikić, Kevin M Ryan, Sharon Tooze
exaly  

DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4

Molecular Cell, 2018
Xin Jin, Heshui Wu, Liguo Wang
exaly  

Brd4 modulates the innate immune response through Mnk2–eIF4E pathway-dependent translational control of IκBα

Proceedings of the National Academy of Sciences of the United States of America, 2017
Jinjing Chen, Jianjun Cheng, Lin-Feng Chen   +2 more
exaly  

Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons

Molecular Cell, 2020
In-Hyun Park, Gareth J. Sullivan, Sang-Hun Lee   +2 more
exaly  

The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response

Cell Death and Disease, 2014
Holger Sültmann, Martin Kerick, Bernd Timmermann   +2 more
exaly