Results 171 to 180 of about 19,105 (226)

Structural Basis for BD1-Preferring 2,4-Disubstituted Pyrimidine BRDT Inhibitors. [PDF]

J Med Chem
Liang T, Guan X, Chan A, Kalra P, Shi R, Solberg J, Sigua LH, Qi J, Pomerantz WCK, Schönbrunn E, Hawkinson JE, Georg GI.   +11 more
europepmc   +1 more source

Esterase-responsive albumin-binding PROTAC-mediated BRD4 degradation for cancer immunotherapy. [PDF]

Theranostics
Lee H, Jeong S, Park J, Son HJ, Kweon S, Lee SS, Shim N, Oh Y, Kang H, Lee C, Lee J, Kim J, Cho H, Kim K.   +13 more
europepmc   +1 more source

Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer. [PDF]

Oncogene
Spellecy O, Qadir J, Han R, Zhu K, Xu B, Zhang Y, Aryal I, Lin RL, Lin AH, Faisal ASM, Napier D, Piecoro D, Scott T, Lin P, Chen L, Brewer LD, Wang C, Kyprianou N, Guo Z, Guo R, Thibault O, Yang BB, Yang XH.   +22 more
europepmc   +1 more source

Epigenetically controlled endothelial promyelocytic leukemia drives liver inflammation and fibrosis. [PDF]

J Clin Invest
Gan C, Lai E, Tai Y, Chen S, Zhao C, Dai W, Yang Z, Li B, Lan T, Xiao Y, Guo Y, Chen J, Wei B, Che Z, Cao S, Liu M, Tacke F, Tang C, Shah VH, Yu H, Wang F, Huang Z, Gao J.   +22 more
europepmc   +1 more source

Cartilage targeting hydrogel nanoplatform degrades BRD4 to alleviate osteoarthritis via Nav1.7 axis. [PDF]

Nat Commun
Zhao Q, Xu T, Du Z, Lu X, Zhang Y, Peng L, Gao Z, Wang W, Zhu B, Liu Z, Yang G, Zhao H, Song Z, Lou Q, Li J, Ren Z, Yu Z, Wang W, Liu Y, Liang H, de la Fuente JM, Cui D.   +21 more
europepmc   +1 more source

BRD4/NUTM1 Fusion Protein [PDF]

, 2020
openaire   +1 more source

Histone acetylation-dependent clustering of BRD2 instructs transcription dynamics. [PDF]

Nat Genet
Erdogdu NU, Guhathakurta S, Oellers R, Shvedunova M, Morin JA, Patrick EM, Seyfferth J, Deboutte W, Gomez-Auli A, Mittler G, Cissé II, Akhtar A.   +11 more
europepmc   +1 more source

BRD4/NUTM1 Fusion Gene [PDF]

, 2020
openaire   +1 more source

SHP2 suppressed the progression of IL-1β induced cartilage damage via modulating BRD4 associated autophagy and pyroptosis signaling pathway. [PDF]

Sci Rep
Zhao Z, Yu X, Zhao F, Li J.
europepmc   +1 more source