Results 151 to 160 of about 20,494 (185)

Self-assembled nano-PROTACs potentiate colorectal cancer immunotherapy via downregulating PD-L1 and GPX4 expression. [PDF]

Mater Today Bio
Luo X, Liu Y, Chen G, Ma X, Xu P, Li Y, Zheng L, Zheng R, Xu Y, Li S, Zhao L.   +10 more
europepmc   +1 more source

Precision-Engineered PROTACs: Integrating Physical and Chemical Strategies for Targeted Cancer Therapy. [PDF]

Small
Yao H, Zhang Y, Zhao H, Liu M, Liu C, Wang P, Chen W, Guo Z, Xing D, Yang J, Li B, Wang C.   +11 more
europepmc   +1 more source

PAX3-FOXO1 Contacts BRD4 through Its Acetylated Intrinsically Disordered Region. [PDF]

Biochemistry
Fraser OA, Schleicher MN, Pagano ML, Showalter SA.   +3 more
europepmc   +1 more source

POLY-Senolytic nanoplatform for tumor-specific eradication of senescent tumor cells and mitigation of radiotherapy-induced immune resistance of cancer. [PDF]

Nat Commun
Lai Y, Zhang S, Pan J, Lan W, Li M, Zhu Z, Xu L, De Geest BG, Lammers T, Zhang W, Yu H, Xu Z.   +11 more
europepmc   +1 more source

The CTNNB1-TRIM28 complex governs hormone-induced RNA polymerase II dynamics in kidney epithelial cells. [PDF]

Proc Natl Acad Sci U S A
Jang HJ, Park E, Jung HJ, Kwon TH.
europepmc   +1 more source

Design of Synthesizable PROTACs through Synthesis Constrained Generative Model and Reinforcement Learning. [PDF]

JACS Au
Xu M, Huang C, Pang L, Deng Q, Zhang H, Qiao A, Luo Z, Wang Z, Hsieh CY, Zhang Z, Chen TG, Chen H, Lei J.   +12 more
europepmc   +1 more source

Sinusoidal endothelial cells control liver inflammation and fibrosis. [PDF]

J Clin Invest
Chen Y, He Y.
europepmc   +1 more source

Synergistic interaction between the macrophage polarizing signals IL-4 and IFNγ is controlled by the STAT6/STAT1/IRF1 axis. [PDF]

Nucleic Acids Res
Varga Z, Poscher A, Váradi EA, Cinege G, Izsán A, Erdős E, Benyhe-Kis B, Tihanyi AZ, Tzerpos P, Bene K, Halász L, Gémes N, Neuperger P, Tóth M, Migh E, Póliska S, Szebeni GJ, Walter JE, Dániel B, Csörgő B, Nagy L, Czimmerer Z.   +21 more
europepmc   +1 more source

Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation. [PDF]

PLoS Pathog
Chen J, Fan J, Qin M, Lin Z, Mu S, Dai L, Qin Z.   +6 more
europepmc   +1 more source

Erratum for the Research Article, "Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription" by D. Cameron <i>et al</i>.

Sci Adv
europepmc   +1 more source