Results 31 to 40 of about 1,922,299 (197)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

A Comparison of Electrical Breakdown Models for Polyethylene Nanocomposites

open access: yesApplied Sciences, 2022
The development of direct current high-voltage power cables requires insulating materials having excellent electrically insulation properties.
Zhaoliang Xing   +5 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Hierarchical fiber bundle strength statistics [PDF]

open access: yes, 2012
Multi-scale modeling is currently one of the most active research topics in a wide range of disciplines. In this thesis we develop innovative hierarchical multi-scale models to analyze the probabilistic strength of fiber bundle structures.
Alsaeed Mahmoud Abdalrahman, Tamer
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

High temperature vulcanized ethylene propylene diene rubber nanocomposites as high voltage insulators: Dielectric breakdown measurements and evaluation

open access: yesPolymers and Polymer Composites, 2022
The use of porcelain and thermoplastic based materials as High voltage insulators has always been dominant in the industry. Several elastomers were also investigated, mainly Ethylene Propylene Rubber and Silicone rubbers were used as replacement of the ...
Ahmed I Abou-Kandil   +2 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Optical studies of the pre-breakdown mechanism in dielectronic liquids. [PDF]

open access: yes, 1977
PhDThe work described in this thesis provides an optical study of pre-breakdown events in liquid dielectrics. A small scale rig employing a 50SI test cell with viewing windows, as part of a high voltage co-axial line, enabled short rise time pulses ...
McGrath, P. B.
core   +4 more sources

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

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