Results 91 to 100 of about 918,929 (287)
Breaking Limits of Line-of-Sight Mimo Capacity in 6G Wireless Communications
Multiple-input-multiple-output (MIMO) has been proved its success for the fourth generation (4G) long term evolution (LTE) and is one of the key technical enablers for evolved mobile broadband (eMBB) in the fifth generation (5G) wireless communications.
Haiyue Jing +2 more
openaire +2 more sources
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Graphene-Enhanced CuW Composites for High-Voltage Circuit Breaker Electrical Contacts
To address the issue of over-standard short-circuit currents in a power system, it is imperative to enhance the comprehensive performance of the electrical contacts, which serve as the lynchpin of circuit breakers, so as to improve the breaking capacity ...
Tan Liu +6 more
doaj +1 more source
Optical meta-atom for localization of light with quantized energy
The capacity to confine light into a small region of space is of paramount importance in many areas of modern science. Here, we suggest a mechanism to store a quantized "bit" of light - with a very precise amount of energy - in an open core-shell ...
Lannebère, Sylvain +1 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Level density and thermal properties in rare earth nuclei
A convergent method to extract the nuclear level density and the gamma-ray strength function from primary gamma-ray spectra has been established. Thermodynamical quantities have been obtained within the microcanonical and canonical ensemble theory ...
A. Gilbert +37 more
core +1 more source
Research on the Technology of Breaking the Shannon Channel Capacity and Shannon Limit
Abstract In this paper, firstly, the Shannon channel capacity is briefly stated, and the relationship between it and the signal uncertainty principle is analyzed in order to prepare for deriving the formula which can break through the Shannon channel capacity.
Dequn Liang, Xinyu Dou
openaire +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source

