Results 101 to 110 of about 32,784 (274)

Sudden visual loss as an initial manifestation of chronic myeloid leukemia

Saudi Journal of Medicine and Medical Sciences, 2017
Chronic myelogenous leukemia (CML) is a pluripotent stem cell disease characterized by anemia, granulocytosis and granulocytic immaturity, basophilia, thrombocytosis and splenomegaly.
Ahmed N Buzaid, Ali M Al-Amri
doaj   +1 more source

Numerical simulation of a supersonic ejector for vacuum generation with explicit and implicit solver in openfoam [PDF]

, 2019
Supersonic ejectors are used extensively in all kind of applications: compression of refrigerants in cooling systems, pumping of volatile fluids or in vacuum generation. In vacuum generation, also known as zero-secondary flow, the ejector has a transient
Camacho, Sergi, Castilla López, Roberto, Codina Macià, Esteban, Gámez Montero, Pedro Javier, Macià Cid, Llorenç   +4 more
core   +2 more sources

Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma

The Journal of Pathology, EarlyView.
Abstract Osteoid osteoma and osteoblastoma are non‐malignant bone‐forming tumours of the skeleton, characterised by the presence of irregular trabeculae of woven bone. Rearrangements in FOS, and less frequently FOSB, have recently been identified in osteoid osteoma and osteoblastoma.
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy van den Akker, David GP van IJzendoorn, Harald MM Mikkers, Hailiang Mei, Anne‐Marie Cleton‐Jansen, Marieke L Kuijjer, Karoly Szuhai, Judith VMG Bovée   +10 more
wiley   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

The chromosome translocation (11;14)(p13;q11) associated with T-cell acute lymphocytic leukemia: an 11p13 breakpoint cluster region [PDF]

, 1989
G Yoffe, N Schneider, L Van Dyk, CY Yang, Michael J. Siciliano, G. N. Buchanan, J. Donald Capra, Richard Baer   +7 more
openalex   +3 more sources

Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations

eLife, 2018
Chromosomal translocations are hallmarks of various types of cancers and leukemias. However, the molecular mechanisms of chromosome translocations remain largely unknown.
Jiying Sun, Lin Shi, Aiko Kinomura, Atsuhiko Fukuto, Yasunori Horikoshi, Yukako Oma, Masahiko Harata, Masae Ikura, Tsuyoshi Ikura, Roland Kanaar, Satoshi Tashiro   +10 more
doaj   +1 more source

Drug‐induced interstitial lung disease associated with dasatinib coinciding with active tuberculosis

Respirology Case Reports, 2020
A 69‐year‐old woman was diagnosed with a breakpoint cluster region‐Abelson‐positive chronic myeloid leukaemia and treated with dasatinib for 14 months. She presented with one month of high‐grade fever and persistent dry cough.
Nozomi Tani, Yusuke Kunimatsu, Izumi Sato, Yuri Ogura, Kazuki Hirose, Takayuki Takeda   +5 more
doaj   +1 more source

CRPPA exon 6–9 deletion as a founder mutation in Chinese patients with dystroglycanopathy

Pediatric Investigation, EarlyView.
Analysis of sixteen Chinese dystroglycanopathy patients reveals a founder mutation (CRPPA exon 6–9 deletion) in 25% of cases and expands the phenotypic spectrum from severe muscle‐eye‐brain disease to limb‐girdle muscular dystrophy. ABSTRACT Importance Dystroglycanopathies (DGPs) are a group of muscular dystrophies with abnormal glycosylation of ...
Jihang Luo, Yidan Liu, Danyu Song, Shiqi Yang, Xiaona Fu, Lin Ge, Cuijie Wei, Liya Cui, Yanbin Fan, Huaxia Luo, Yanwei He, Jin Xu, Qiang Shen, Yuxuan Guo, Motoi Kanagawa, Tatsushi Toda, Jingmin Wang, Hong Zhang, Hui Xiong   +18 more
wiley   +1 more source

FISH mapping of Philadelphia negative BCR/ABL1 positive CML

Molecular Cytogenetics, 2008
Background Chronic myeloid leukaemia (CML) is a haematopoietic stem cell disorder, almost always characterized by the presence of the Philadelphia chromosome (Ph), usually due to t(9;22)(q34;q11) or its variants.
Marin David, De Melo Valeria AS, Chanalaris Anastasios, Valgañón Mikel, Howard-Reeves Julie, Reid Alistair G, Brazma Diana, Virgili Anna, Apperley Jane F, Grace Colin, Nacheva Ellie P   +10 more
doaj   +1 more source

In vitro evaluation of azole fungicide sensitivity in Fusarium langsethiae, F. tricinctum, F. poae and F. sporotrichioides populations from Irish oats

Pest Management Science, EarlyView.
Microtitre plate assays of 286 Irish oat isolates show species‐specific azole sensitivity. In Fusarium langsethiae, mefentrifluconazole and tebuconazole sensitivities correlate, defining four phenotypes and supporting resistance monitoring and integrated control.
Diana E. Bucur, Steven Kildea
wiley   +1 more source