Philadelphia-positive chronic myeloid leukemia with a chromosome 22 breakpoint outside the breakpoint cluster region [published erratum appears in Blood 1988 Jan;71(1):272] [PDF]
Licia Selleri +8 more
openalex +3 more sources
Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL-USP2 fusions. [PDF]
Meyer C +28 more
europepmc +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Breakpoint cluster region (BCR; BCR-ABL1); v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC); mammalian target of rapamycin (mTOR; FRAP; RAFT1); kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR); phosphoinositide 3-kinase (PI3K) [PDF]
openalex +1 more source
Coastal dissolved organic carbon (DOC) represents one of the largest reduced carbon pools on Earth, and they are influenced by temperature. Across 7.6–35.9 °C ranges, the microbial‐mediated DOC dynamics is characterized by three temperature thresholds.
Junfu Dong +12 more
wiley +1 more source
Chronic Myeloid Leukemia with Rare e1a3 BCR-ABL Transcript
Chronic myelogenous leukemia (CML) results from neoplastic transformation of a hematopoietic stem cell. It is cytogenetically characterized by the presence of Philadelphia chromosome which results from reciprocal translocation t(9;22) that juxtaposes ...
Najia Tabassum +3 more
doaj
BRIGHT is a newly developed live‐cell imaging system that integrates cascade amplification with background denoising through the bivalent binding capability and antigen‐dependent stability of a bivalent fluorescent nanobody targeting ALFA peptides.
Lei Feng +9 more
wiley +1 more source
Early T cell differentiated chronic myeloid leukemia blast crisis with rearrangement of the breakpoint cluster region but not of the T cell receptor beta chain genes [PDF]
Martin Gramatzki +5 more
openalex +1 more source

