Results 151 to 160 of about 160,061 (270)

Population Divergence in the Eastern North American Boreal Forests: Extensive Gene Flow Characterises a Hybrid Zone Between Palm Warbler Subspecies (Parulidae: Setophaga palmarum)

Molecular Ecology, EarlyView.
ABSTRACT Pleistocene glaciations have shaped much of the population divergence events in the coniferous forests of North America. However, unlike in western North America, the evidence for forest fragmentation and population divergence associated with glacial cycles is less clear in the boreal forests of eastern North America.
Gihyun Yoo, Jason T. Weir
wiley   +1 more source

A near‐gapless genome assembly of Pseudocydonia sinensis uncovers unique phenylpropanoid pathways

Plant Biotechnology Journal, EarlyView.
Summary Pseudocydonia sinensis, commonly known as Chinese quince, belongs to the Rosaceae family and is closely related to apple and pear. Despite its botanical significance, genomic resources for this species remain limited. We present a high‐quality, chromosome‐scale, and haplotype‐resolved genome assembly of P.
Yangxin Zhang, Shuangyu Zhang, Wenmeng Guo, Yuxin Zhang, Xiangxiang Chen, Qiaoming Yu, Yunxiao Liu, Yaqiang Sun, Ke Yu, Houhua Li, Fengwang Ma, Tao Zhao   +11 more
wiley   +1 more source

Single Monochrome Real-Time RT-PCR Assay for Identification, Quantification, and Breakpoint Cluster Region Determination of t(9;22) Transcripts [PDF]

, 2005
Marina Gutiérrez, Georgina Timson, Abdul K. Siraj, Rong Bu, Shakuntala Barbhaya, Sripad Banavali, Kishor Bhatia   +6 more
openalex   +1 more source

Largest genome assembly in Brassicaceae: retrotransposon‐driven genome expansion and karyotype evolution in Matthiola incana

Plant Biotechnology Journal, EarlyView.
Summary Matthiola incana, commonly known as stock and gillyflower, is a widely grown ornamental plant whose genome is significantly larger than that of other species in the mustard family. However, the evolutionary history behind such a large genome (~2 Gb) is still unknown.
Daozong Chen, Taihua Yang, Haidong Chen, Xiaohan Zhang, Fan Huang, Shubei Wan, Zhanjun Lu, Chao Liu, Yong Lei, Huifang Jiang, Boshou Liao, Graham J. King, Martin A. Lysak, Chen Tan, Xianhong Ge   +14 more
wiley   +1 more source

The use of public spatial databases in risk analysis: A US‐oriented tutorial

Risk Analysis, EarlyView.
Abstract This tutorial focuses on opportunities and challenges associated with using six large, publicly accessible spatial databases published during the last decade by US federal agencies. These databases provide opportunities for researchers to risk‐inform policy by comparing community asset, demographic, economic, and social data, along with ...
Michael R. Greenberg, Dona Schneider, Louis Anthony Cox Jr.   +2 more
wiley   +1 more source

Cell lineage tracing: Methods, applications, and challenges

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cell lineage tracing is a crucial technique for understanding cell fate and lineage relationships, with wide applications in developmental biology, tissue regeneration, and disease progression studies. Over the years, experimental cell lineage tracing methods have advanced from early labeling techniques to modern genetic tools such as CRISPR ...
Shanjun Mao, Chenyang Zhang, Runjiu Chen, Shan Tang, Xiaodan Fan, Jie Hu   +5 more
wiley   +1 more source

Novel Findings in Pediatric and Adolescent Patients With Cancer and a Germline SMARCA4 Variant

Pediatric Blood &Cancer, Volume 72, Issue 9, September 2025.
ABSTRACT Introduction SMARCA4 is a known susceptibility gene for malignant rhabdoid tumors (MRT) in children and small cell carcinoma of the ovary hypercalcemic type (SCCOHT) in young females and women. Recently, a novel association between germline SMARCA4 variants and predisposition to neuroblastoma was proposed.
Nienke van Engelen, Ronald. R. de Krijger, Michelle M. Kleisman, Lennart. A. Kester, Saskia M. J. Hopman, Mariette E. G. Kranendonk, Marijn A. Vermeulen, Carli Tops, Seok‐Young Kim, Hans Clevers, Kornelia Neveling, Roland. P. Kuiper, Marjolijn C. J. Jongmans   +12 more
wiley   +1 more source

Phenotypic Divergence of JAG1‐ and NOTCH2‐Associated Alagille Syndrome & Disease‐Specific NOTCH2 Variant Classification Guidelines

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background & Aims Alagille syndrome (ALGS) is a rare, autosomal dominant disorder with high phenotypic heterogeneity. Disease‐causing variants are primarily identified in Jagged1 (JAG1), with fewer reported in NOTCH2. JAG1 variants cause disease through a mechanism of haploinsufficiency, but the mechanism for NOTCH2 variants is not completely ...
Shannon M. Vandriel, Li‐Ting Li, Huiyu She, Jian‐She Wang, Kathleen M. Loomes, David A. Piccoli, Irena Jankowska, Piotr Czubkowski, Dorota Gliwicz‐Miedzińska, Lorenzo D'Antiga, Emanuele Nicastro, Florence Lacaille, Dominique Debray, Étienne M. Sokal, Tanguy Demaret, Rima L. Fawaz, Silvia Nastasio, Kyung Mo Kim, Seak Hee Oh, Björn Fischler, Henrik Arnell, Catherine Larson‐Nath, Winita Hardikar, Sahana Shankar, Shikha S. Sundaram, Alexander Chaidez, Pinar Bulut, Pier Luigi Calvo, Mureo Kasahara, Niviann Blondet, Eberhard Lurz, Anna‐Maria Kavallar, Emmanuel M. Gonzales, Emmanuel Jacquemin, Jérôme Bouligand, Noelle H. Ebel, Jeffrey A. Feinstein, Susan M. Siew, Michael O. Stormon, Saul J. Karpen, Rene Romero, M. Kyle Jensen, Catalina Jaramillo, James E. Squires, Sarah M. Bedoyan, Deirdre A. Kelly, Jane Hartley, Henkjan J. Verkade, Way Seah Lee, Chatmanee Lertudomphonwanit, Ryan T. Fischer, Henry C. Lin, Nathalie Rock, Yael Mozer‐Glassberg, Amin J. Roberts, Helen M. Evans, Wikrom Karnsakul, Gabriella Nebbia, Victorien M. Wolters, Pamela L. Valentino, Jesus Quintero Bernabeu, Amal A. Aqul, Cigdem Arikan, María Legarda Tamara, Cristina Molera Busoms, Thomas Damgaard Sandahl, Giuseppe Indolfi, Andréanne N. Zizzo, Aglaia Zellos, Ruben E. Quiros‐Tejeira, Ermelinda Santos‐Silva, Kathleen B. Schwarz, Jernej Brecelj, Maria Camila Sanchez, Maria Lorena Cavalieri, Christos Tzivinikos, Sabina Wiecek, John Eshun, Nanda Kerkar, Quais Mujawar, Zerrin Önal, Cristina Gonçalves, Jennifer Garcia, Seema Alam, Carolina Jimenez‐Rivera, Luis Bujanda, Richard J. Thompson, Bettina E. Hansen, Nancy B. Spinner, Melissa A. Gilbert, Binita M. Kamath, The Global ALagille Alliance (GALA) Study Group   +91 more
wiley   +1 more source

Prevalence of Antimicrobial Resistance in Klebsiella pneumoniae in the South African Populations: A Systematic Review and Meta‐Analysis of Surveillance Studies

MicrobiologyOpen, Volume 14, Issue 4, August 2025.
Klebsiella pneumoniae isolates in South Africa exhibit > 50% resistance to first‐line antibiotics, with rising carbapenem resistance. Urgent, targeted interventions and genomic surveillance are essential to curb the spread of multidrug‐resistant strains and preserve treatment efficacy.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

A computational dynamic model of combination treatment for type II inhibitors with asciminib

Protein Science, Volume 34, Issue 8, August 2025.
Abstract Despite continuous strides forward in drug development, resistance to treatment looms large in the battle against cancer as well as communicable diseases. Chronic myeloid leukemia (CML) is treated with targeted therapy and treatment is personalized when resistance arises.
J. Roadnight Sheehan, Astrid S. de Wijn, Ran Friedman   +2 more
wiley   +1 more source