Dasatinib-induced massive left chylothorax in a patient with chronic myeloid leukemia
Respiratory Medicine Case Reports, 2022 Dasatinib, an effective second-generation tyrosine kinase inhibitor, is used to treat breakpoint cluster region-Ableson-positive chronic myeloid leukemia or Philadelphia chromosome-positive acute lymphocytic leukemia.
Go Makimoto +3 more
doaj +1 more source
Extinctions of aculeate pollinators in Britain and the role of large-scale agricultural changes [PDF]
, 2014 Pollinators are fundamental to maintaining both biodiversity and agricultural productivity, but habitat destruction, loss of flower resources, and increased use of pesticides are causing declines in their abundance and diversity. Using historical records
Biesmeijer +8 more
core +1 more source
PLoS Genetics, 2012 Mutations in the BREVIPEDICELLUS (BP) gene of Arabidopsis thaliana condition a pleiotropic phenotype featuring defects in internode elongation, the homeotic conversion of internode to node tissue, and downward pointing flowers and pedicels.
Joelle S dela Paz +5 more
doaj +1 more source
PCR detection of a Maell polymorphism in the human major breakpoint cluster region (BCR)
Nucleic Acids Research, 1991 J.S. McMlure, Craig E. Litz
openalex +5 more sources
p185(BCR/ABL) has a lower sensitivity than p210(BCR/ABL) to the allosteric inhibitor GNF-2 in Philadelphia chromosome-positive acute lymphatic leukemia [PDF]
, 2011 Background: The t(9;22) translocation leads to the formation of the chimeric breakpoint cluster region/c-abl oncogene 1 (BCR/ABL) fusion gene on der22, the Philadelphia chromosome.
Mahajna, Jamal +5 more
core +2 more sources
High-Mass Proto-Stellar Candidates - II : Density structure from dust continuum and CS emission [PDF]
, 2001 We present a detailed 1.2 mm continuum and CS spectral line study of a large sample of 69 massive star forming regions in very early stages of evolution, most of them prior to building up an ultracompact HII region.
Bacmann A. +23 more
core +2 more sources
Aphidicolin-Induced FRA3B Breakpoints Cluster in Two Distinct Regions
Genomics, 1997 The common fragile site at chromosomal band 3p14.2 (FRA3B) is the most sensitive single site in the human genome to induced chromosomal lesions. This fragile site may predispose chromosome 3p to breakage that is commonly observed in lung, renal, and many other cancers.
L, Wang +7 more
openaire +2 more sources
Leukemia Research Reports, 2019 In this work, we analyzed the association between RUNX1 gene expression and the accessibility of BCR3, one of RUNX1 gene breakpoint regions involved in the chromosomal translocation (8;21), a frequent translocation in treatment-related acute myeloid ...
Nicolás Schnake, Soraya Gutiérrez
doaj +1 more source
The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice. [PDF]
, 2012 The PICALM (CALM) gene, whose product is involved in clathrin-mediated endocytosis, has been identified in two recurring chromosomal translocations, involving either MLL or MLLT10 (AF10). We developed a mouse model of CALM-AF10(+) leukemia to examine the
Anastasi, J +5 more
core +2 more sources
Design and realization of precise indoor localization mechanism for Wi-Fi devices [PDF]
, 2016 Despite the abundant literature in the field, there is still the need to find a time-efficient, highly accurate, easy to deploy and robust localization algorithm for real use. The algorithm only involves minimal human intervention. We propose an enhanced
Calveras Augé, Anna M. +5 more
core +1 more source