Results 31 to 40 of about 30,324 (227)

A dual origin for Bcr-Abl gene translocation/fusion as dynamics of synergism of the hematopoietic stem cell and hemangioblast in chronic myeloid leukemia [PDF]

, 2015
Contextual BCR-ABL tyrosine kinase over-activity determines in formulated fashion the emergence of proliferation and anti-apoptosis that arise largely as derived phenomena of otherwise homeostatic mechanisms of the c-ABL gene within hematopoietic ...
Agius, Lawrence M.
core   +1 more source

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

Advanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang, Xiaofei Wang, Chengli Liu, Kaixuan He, Xiu‐Li Hou, Haofei Luo, Shuaibin Zhang, Changqing You, Yajun Jia, Fuqiang Wang, Xianwei Song, Guodao Liu, Xian Deng, Xiaofeng Cao   +13 more
wiley   +1 more source

Lazy Probabilistic Model Checking without Determinisation [PDF]

, 2015
The bottleneck in the quantitative analysis of Markov chains and Markov decision processes against specifications given in LTL or as some form of nondeterministic B\"uchi automata is the inclusion of a determinisation step of the automaton under ...
Hahn, Ernst Moritz, Li, Guangyuan, Schewe, Sven, Turrini, Andrea, Zhang, Lijun   +4 more
core   +2 more sources

Protected Chaos in a Topological Lattice

Advanced Science, EarlyView.
Topological and chaotic dynamics are often considered incompatible, with one expected to dominate or disrupt the other. This work reveals that topological localization can persist even under strong chaotic dynamics and, counter‐intuitively, protect chaotic behavior.
Haydar Sahin, Hakan Akgün, Zhuo Bin Siu, S. M. Rafi‐Ul‐Islam, Jian Feng Kong, Mansoor B. A. Jalil, Ching Hua Lee   +6 more
wiley   +1 more source

Identification of the TCL6 genes within the breakpoint cluster region on chromosome 14q32 in T-cell leukemia [PDF]

Oncogene, 2000
A region on chromosome 14q32.1 is often involved in chromosomal translocations and inversions with one of the T-cell receptor loci in T-cell lymphoproliferative diseases. The breakpoints of the different rearrangements segregate into two clusters; a cluster due to inversion on the centromeric side and a cluster due to simple balanced translocations on ...
Toyomasa Hatakeyama, Giandomenico Russo, Masumichi Saitou, Masaharu Isobe, Jun Sugimoto   +4 more
openaire   +3 more sources

Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle

Advanced Science, EarlyView.
This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia, Fuwen Wang, Xiaoyu Luo, Shuang Li, Yang Lyu, Yining Zheng, Zhijie Ma, Kaixing Qu, Rende Song, Jianyong Liu, Jicai Zhang, Basang Wangdui, Basang Zhuzha, Suolang Quji, Li Zhao, Silang Wangmu, Ciren Luobu, Nima Cangjue, Danzeng Luosang, Suolang Sizhu, Haijian Cheng, Ruizhe Li, Zhipeng Wu, Ruihua Dang, Yongzhen Huang, Xianyong Lan, Luohao Xu, Haifei Hu, WaiYee Low, Zhuqing Zheng, Yu Wang, Yuanpeng Gao, Lu Deng, Johannes A. Lenstra, Jianlin Han, Xueyi Yang, Wenfa Lyu, Bizhi Huang, Chuzhao Lei, Ningbo Chen   +39 more
wiley   +1 more source

Measurement of the electric fluctuation spectrum of magnetohydrodynamic turbulence

, 2005
Magnetohydrodynamic (MHD) turbulence in the solar wind is observed to show the spectral behavior of classical Kolmogorov fluid turbulence over an inertial subrange and departures from this at short wavelengths, where energy should be dissipated.
Bieber, F. S. Mozer, H. Reme, H. J. Beinroth, P. J. Kellogg, P. C. Filbert, S. D. Bale, T. S. Horbury   +7 more
core   +1 more source

Mitigating Cell Cycle Effects in Multi‐Omics Data: Solutions and Analytical Frameworks

Advanced Science, EarlyView.
The study highlights the cell‐cycle effects on multi‐omics analysis attributed to varying cell cycle compositions across cell types. To minimize the influence, we propose RTD correction in CNV calling with a high S‐phase ratio, and phase comparison in chromatin accessibility, DNA methylation, and transcriptomics.
Rui Nie, Caihong Zheng, Likun Ren, Yue Teng, Yaoyu Sun, Lifei Wang, Junya Li, Jun Cai   +7 more
wiley   +1 more source

Evolutionary patchwork of an insecticidal toxin shared between plant-associated pseudomonads and the insect pathogens Photorhabdus and Xenorhabdus [PDF]

, 2015
Background: Root-colonizing fluorescent pseudomonads are known for their excellent abilities to protect plants against soil-borne fungal pathogens. Some of these bacteria produce an insecticidal toxin (Fit) suggesting that they may exploit insect hosts ...
Bloemberg, Guido, Grunder, Juerg, Höfte, Monica, Keel, Christoph, Maurhofer, Monika, Pechy-Tarr, Maria, Ruffner, Beat   +6 more
core   +3 more sources

Multicluster Distributed Optimization Strategy for Turbine Wake Environment

Advanced Intelligent Systems, EarlyView.
This article studies the wake analysis of wind farms in different aspects, including basic methods, clustering optimization, and wake optimization. Through multiclustering, the wake optimization in a specific wind farm environment is explored. And focusing on the time cost and other issues that need to be solved in practical applications, targeted ...
Zhenping Yu, Xinmeng Zhou, Yedong Huang, Kunyu Zhou, Guangming Cui, Juntian Qu   +5 more
wiley   +1 more source