Results 51 to 60 of about 32,784 (274)
Genomic EWS-FLI1 fusion sequences in Ewing sarcoma resemble breakpoint characteristics of immature lymphoid malignancies. [PDF]
PLoS ONE, 2013 Chromosomal translocations between the EWS gene and members of the ETS gene family are characteristic molecular features of the Ewing sarcoma. The most common translocation t(11;22)(q24;q12) fuses the EWS gene to FLI1, and is present in 85-90% of Ewing ...
Manfred Berger +6 more
doaj +1 more source
Statistical Analysis of Water Masers in Star-Forming Regions: Cepheus A and W75 N [PDF]
, 2010 We have done a statistical analysis of Very Long Baseline Array (VLBA) data of water masers in the star-forming regions (SFRs) Cepheus A and W75 N, using correlation functions to study the spatial clustering and Doppler-velocity distribution of these ...
Anglada, G. +7 more
core +2 more sources
Journal of Biomedical Science, 2010 Background Nasopharyngeal carcinoma (NPC) is commonly found in Southern China and South East Asia. Epstein-Barr virus (EBV) infection is well associated with NPC and has been implicated in its pathogenesis.
Sim Sai-Peng, Yee Peter
doaj +1 more source
Update in Childhood Chronic Myeloid Leukemia
Hemato, 2022 Chronic myeloid leukemia (CML) in childhood represents only 3% of newly diagnosed pediatric leukemia. The diagnostic hallmark of CML is the Philadelphia (Ph) chromosome, which derives from the fusion of the ABL1-oncogene located on chromosome 9 to the ...
Fiorina Giona, Simona Bianchi
doaj +1 more source
Measurement of the electric fluctuation spectrum of magnetohydrodynamic turbulence
, 2005 Magnetohydrodynamic (MHD) turbulence in the solar wind is observed to show the spectral behavior of classical Kolmogorov fluid turbulence over an inertial subrange and departures from this at short wavelengths, where energy should be dissipated.
Bieber +7 more
core +1 more source
Discovery of large genomic inversions using long range information. [PDF]
, 2017 BackgroundAlthough many algorithms are now available that aim to characterize different classes of structural variation, discovery of balanced rearrangements such as inversions remains an open problem.
Alkan, Can +8 more
core +3 more sources
Frontiers in Genetics, 2016 Copy-number variation (CNV) has been associated with increased risk of complex diseases. High throughput sequencing (HTS) technologies facilitate the detection of copy-number variable regions (CNVRs) and their breakpoints.
HOANG T NGUYEN +10 more
doaj +1 more source
Respirology Case Reports, 2021 Dasatinib is a potent and effective second‐generation oral tyrosine kinase inhibitor that is clinically indicated for the treatment of imatinib‐resistant or imatinib‐intolerant breakpoint cluster region‐Abelson (BCR‐ABL)‐positive chronic myeloid ...
Chao‐Chin Hsu +2 more
doaj +1 more source
ViFi: accurate detection of viral integration and mRNA fusion reveals indiscriminate and unregulated transcription in proximal genomic regions in cervical cancer. [PDF]
, 2018 The integration of viral sequences into the host genome is an important driver of tumorigenesis in many viral mediated cancers, notably cervical cancer and hepatocellular carcinoma.
Bafna, Vineet +4 more
core +1 more source
Frontiers in Oncology, 2015 Ionizing radiation generates DNA double-strand breaks (DSB) which, unless faithfully repaired, can generate chromosomal rearrangements in hematopoietic stem and/or progenitor cells (HSPC), potentially priming the cells towards a leukemic phenotype. Using
Melanie eRall +8 more
doaj +1 more source