Results 81 to 90 of about 30,324 (227)

Market Potential, Road Accessibility, and Firm Births: Evidence From 20 Years of Road Investment

Journal of Regional Science, EarlyView.
ABSTRACT This paper investigates the causal effects of road accessibility, measured by market potential, on firm births in Portuguese municipalities between 1991 and 2016, a period marked by significant road improvements. We address the endogeneity of market potential by employing instrumental variables within Poisson Pseudo‐maximum Likelihood ...
Mauricio S. de Carvalho, Patrícia C. Melo, Bruno T. Rocha, Isabel Proença, João de Abreu e Silva   +4 more
wiley   +1 more source

Successful Treatment of a Patient with Chronic Myelogenous Leukemia with Concurrent Janus Kinase 2 (JAK2) R795S Mutation and Breakpoint Cluster Region-ABL1 (BCR-ABL1) Fusion: A Case Report and Literature Review. [PDF]

Am J Case Rep, 2020
Yue Y, Wei W, Guo Y, Wang F, Dong W, Liu Y, Lin Y, Cao Y, Gu W.   +8 more
europepmc   +1 more source

Limited genomic signatures of population collapse in the critically endangered black abalone (Haliotis cracherodii)

Molecular Ecology, EarlyView.
Abstract The black abalone, Haliotis cracherodii, is a large, long‐lived marine mollusc that inhabits rocky intertidal habitats along the coast of California and Mexico. In 1985, populations were impacted by a bacterial disease known as withering syndrome (WS) that wiped out >90% of individuals, leading to the closure of all U.S.
Brock Wooldridge, Chloé Orland, Erik Enbody, Merly Escalona, Cade Mirchandani, Russell Corbett‐Detig, Joshua D. Kapp, Nathaniel Fletcher, Karah Cox‐Ammann, Peter Raimondi, Beth Shapiro   +10 more
wiley   +1 more source

Genome‐Wide Population Structure in a Marine Keystone Species, the European Flat Oyster (Ostrea edulis)

Molecular Ecology, EarlyView.
ABSTRACT Ostrea edulis, the European flat oyster, was once a widespread economically and ecologically important marine species, but has suffered dramatic declines over the past two centuries. Consequently, there has been a surge in European restoration efforts, many of which focus on restocking as a conservation measure.
Homère J. Alves Monteiro, Dorte Bekkevold, George Pacheco, Stein Mortensen, Runyang Nicolas Lou, Nina O. Therkildsen, Arnaud Tanguy, Chloé Robert, Pierre De Wit, Dorte Meldrup, Ane T. Laugen, Philine S. E. zu Ermgassen, Åsa Strand, Camille Saurel, Jakob Hemmer‐Hansen   +14 more
wiley   +1 more source

The Evolution of Locally Adaptive Chromosome Inversions in Mimulus guttatus

Molecular Ecology, EarlyView.
ABSTRACT Chromosomal inversion polymorphisms are ubiquitous across the diversity of diploid organisms and play a significant role in the evolution of adaptations in those species. Inversions are thought to operate as supergenes by trapping adaptive alleles at multiple linked loci through the suppression of recombination. While there is now considerable
Leslie M. Kollar, Lauren E. Stanley, Sunil K. Kenchanmane Raju, David B. Lowry, Chad E. Niederhuth   +4 more
wiley   +1 more source

The Distribution and Dispersal of Large Haploblocks in a Superspecies

Molecular Ecology, EarlyView.
ABSTRACT Haploblocks are regions of the genome that coalesce to an ancestor as a single unit. Differentiated haplotypes in these regions can result from the accumulation of mutational differences in low‐recombination chromosomal regions, especially when selective sweeps occur within geographically structured populations.
Darren Irwin, Staffan Bensch, Caleigh Charlebois, Gabriel David, Armando Geraldes, Sandeep Kumar Gupta, Bettina Harr, Paul Holt, Jessica H. Irwin, Vladimir V. Ivanitskii, Irina M. Marova, Yongchao Niu, Sampath Seneviratne, Ashutosh Singh, Yongjie Wu, Shangmingyu Zhang, Trevor D. Price   +16 more
wiley   +1 more source

Putting Structural Variants Into Practice: The Role of Chromosomal Inversions in the Management of Marine Environments

Molecular Ecology, EarlyView.
ABSTRACT Major threats to marine species and ecosystems include overfishing, invasive species, pollution and climate change. The changing climate not only imposes direct threats through the impacts of severe marine heatwaves, cyclones and ocean acidification but also complicates fisheries and invasive species management by driving species range shifts.
Nadja M. Schneller, Jan M. Strugnell, Matt A. Field, Kerstin Johannesson, Ira Cooke   +4 more
wiley   +1 more source

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. [PDF]

, 2019
Accelerating cures for children with cancer remains an immediate challenge as a result of extensive oncogenic heterogeneity between and within histologies, distinct molecular mechanisms evolving between diagnosis and relapsed disease, and limited ...
Baxter, Patricia, Bendak, Katerina, Berko, Esther R, Bowen, Jay, Braun, Frank K, Bryan, Anthony C, Böhm, Julia W, Cardenas, Maria F, Chen, Yidong, Coppens, Sara E, Cross, Katherine L, Diskin, Sharon J, Doddapaneni, HarshaVardhan, Du, Yunchen, Egolf, Laura E, Evans, Kathryn, Farrel, Alvin, Gaonkar, Krutika S, Gastier-Foster, Julie M, Gatto, Gregory J, Gorlick, Richard, Greene, Casey S, Haber, Michelle, Hart, Lori S, Haussler, David, Houghton, Peter J, Jayaseelan, Joy, Kalletla, Karthik, Kendsersky, Nathan M, Kolb, E Anders, Krytska, Kateryna, Kurmashev, Dias, Kurmasheva, Raushan T, Leraas, Kristen M, Li, Xiao-Nan, Lindsay, Holly B, Lock, Richard B, Lopez, Gonzalo, Maris, John M, Marshall, Glenn M, Mayoh, Chelsea, McCalmont, Hannah, McCoy, Kristyn, Modi, Apexa, Momin, Zeineen, Morton, Christopher, Mosse, Yael P, Nance, Jonas, Patel, Khushbu, Pfeil, Jacob, Qi, Lin, Raman, Pichai, Rathi, Komal S, Reynolds, C Patrick, Rokita, Jo Lynne, Sacks, Gregory I, Sanchez, Yolanda, Shu, Jack, Smith, Malcolm A, Tyrrell, Vanessa, Upton, Kristen A, Vaksman, Zalman, Vaske, Olena Morozova, Way, Gregory P, Wheeler, David A, Zhang, Huiyuan, Zhang, Wendong, Zhao, Sibo, Zheng, Siyuan   +68 more
core  

A Chromosome Inversion Creates a Supergene for Sex and Colour in Lake Malawi Cichlids

Molecular Ecology, EarlyView.
ABSTRACT Cichlid fishes have the highest rates of evolutionary turnover of sex chromosomes among vertebrates. Many large structural polymorphisms in the radiation of cichlids in Lake Malawi are associated with sex chromosomes and may also carry adaptive variation.
Kristen A. Behrens, Soumya Jailwala, Frances E. Clark, Anne C. Meyer, Nikesh M. Kumar, Adrianus F. Konings, Reade B. Roberts, Matthew A. Conte, Jeffrey T. Streelman, Patrick T. McGrath, Thomas D. Kocher   +10 more
wiley   +1 more source

A near‐gapless genome assembly of Pseudocydonia sinensis uncovers unique phenylpropanoid pathways

Plant Biotechnology Journal, EarlyView.
Summary Pseudocydonia sinensis, commonly known as Chinese quince, belongs to the Rosaceae family and is closely related to apple and pear. Despite its botanical significance, genomic resources for this species remain limited. We present a high‐quality, chromosome‐scale, and haplotype‐resolved genome assembly of P.
Yangxin Zhang, Shuangyu Zhang, Wenmeng Guo, Yuxin Zhang, Xiangxiang Chen, Qiaoming Yu, Yunxiao Liu, Yaqiang Sun, Ke Yu, Houhua Li, Fengwang Ma, Tao Zhao   +11 more
wiley   +1 more source