Results 111 to 120 of about 5,403,021 (155)

Endogenous and environmental factors that induce DNA replication defects and genomic instability in ER-negative heterozygous BRCA1 cells. [PDF]

Sci Rep
Deshpande M, Paniza T, Brown R, Heslin K, Patel N, Madireddy A, Rosenwaks Z, Gerhardt J.   +7 more
europepmc   +1 more source

Reproductive Challenges in Mutated BRCA Gene Carriers: A Narrative Review. [PDF]

Curr Issues Mol Biol
Vouza M, Papadoliopoulou M, Dimitrakakis K, Zografos G, Michalopoulos NV, Arkadopoulos N.   +5 more
europepmc   +1 more source

Functional Characterization of <i>POLE1</i> Variant Fibroblasts Reveals Replication Stress and Increased Sensitivity to Genotoxic Stress. [PDF]

Diseases
Khdeda E, Naumann-Bartsch N, Khdeda N, Cramer G, Hildebrand LS, Schiller P, Wagner PJ, Fahrmeier F, Hüffmeier U, Corradini S, Distel LV, Kuhlmann LCF.   +11 more
europepmc   +1 more source

EZH2 deficiency suppresses colorectal cancer progression by inhibiting the mismatch repair pathway and consequently reducing extrachromosomal circular DNA formation. [PDF]

Cell Death Dis
Qiu Q, Ding Y, Han J, Guo X, Zhang J, Chen Y, Xue X, Hu X, Yu T, Liu G, Zhang H, Li Q, Li X, She J, Chen Y.   +14 more
europepmc   +1 more source

RB dependent transcriptional regulation at mitotic centromeres preserves genome stability. [PDF]

Life Sci Alliance
Crowley EA, Manning AL.
europepmc   +1 more source

Dysfunctional DNA Mismatch Repair Drives the Evolution of Gene Amplification in MTX-Resistant Human Colorectal Cancer Cells. [PDF]

Int J Mol Sci
Wang X, Li S, Liu Y, Gao Y, Shi X, Han X, Zhang H, Meng X.   +7 more
europepmc   +1 more source

Replication stress induced exposure to methotrexate in root meristem cells of Vicia faba. [PDF]

Histochem Cell Biol
Aneta Ż, Gocek-Szczurtek N, Wróblewski M, Cieślak K, Polit JT.   +4 more
europepmc   +1 more source

Homozygous FANCM Variant c.5101C>T p.(Gln1701*) in a Patient With Early Onset Breast Cancer, Chemotherapy Toxicity, and Chromosome Fragility: A Case Report. [PDF]

Cancer Rep (Hoboken)
Sulkava S, Hakonen AH, Christensen R, Pöyhönen M, Nevanlinna H.   +4 more
europepmc   +1 more source

Low-dose X-Ray induced genetic damage in human peripheral blood lymphocytes. [PDF]

Front Genet
Villalba-Rondón LC, Vélez-Lemus L, Jaramillo-Garzón W, Pulido-Medellín M, Rangel N, Rondón-Lagos M.   +5 more
europepmc   +1 more source

DHX9 Inhibition Enhances Paclitaxel Sensitivity by Inducing Mitotic Failure in Ovarian and Endometrial Cancers. [PDF]

Mol Cancer Ther
Huang TT, Nair JR, Bowen C, Castro J, Nousome D, Nayak S, Silver SJ, Lee JM.   +7 more
europepmc   +1 more source