Individual Radiosensitivity in Oncological Patients: Linking Adverse Normal Tissue Reactions and Genetic Features [PDF]
Frontiers in Oncology, 2019 Introduction: Adverse effects of radiotherapy (RT) significantly affect patient's quality of life (QOL). The possibility to identify patient-related factors that are associated with individual radiosensitivity would optimize adjuvant RT treatment ...
Elisa Palumbo +13 more
doaj +4 more sources
Individual Radiosensitivity as a Risk Factor for the Radiation-Induced Acute Radiodermatitis [PDF]
Life, 2021 Background: Up to 95% of irradiated patients suffer from ionizing radiation (IR) induced early skin reaction, acute radiation dermatitis (ARD). Some experts think that additional skin hydration can reduce acute skin reactions. Individual radiosensitivity
Juras Kišonas +6 more
doaj +2 more sources
Is in vivo and ex vivo irradiation equally reliable for individual Radiosensitivity testing by three colour fluorescence in situ hybridization? [PDF]
Radiation Oncology, 2019 Background Individual radiosensitivity is influencing the outcome of radiation therapy. A general ex vivo testing is very work-intensive. It is of interest to see if a significant prediction concerning the sensitivity can be made by in vivo irradiation ...
Theresa Mayo +8 more
doaj +2 more sources
Breast cancer risk genes affecting individual radiosensitivity [PDF]
Scientific ReportsIncreased radiosensitivity can cause adverse radiotherapy effects. Heterozygote variants in breast cancer risk genes increase cancer risk and may affect radiosensitivity.
Ramona K. G. Vogel +10 more
doaj +2 more sources
Assessment of Individual Radiosensitivity in Breast Cancer Patients Using a Combination of Biomolecular Markers [PDF]
Biomedicines, 2023 About 5% of patients undergoing radiotherapy (RT) develop RT-related side effects. To assess individual radiosensitivity, we collected peripheral blood from breast cancer patients before, during and after the RT, and γH2AX/53BP1 foci, apoptosis ...
Matus Durdik +11 more
doaj +2 more sources
Chromosomal Radiosensitivity in Sjögren’s Syndrome with and Without Concomitant Malignancy [PDF]
CellsConnective tissue diseases have long been hypothesized to confer increased radiosensitivity and radiotherapy-related toxicity, although findings vary between disease entities.
Elena Strljic +7 more
doaj +2 more sources
Rh factor is associated with individual radiosensitivity: A cytogenetic study [PDF]
Electronic Physician, 2016 Introduction: Radiosensitivity is an inherent trait, associated with a raised reaction to ionizing radiation on the human body. In radiotherapy and radiation protection fields, individualization of the patient’s treatment is one of the main topics ...
Meysam Khosravifarsani +2 more
doaj +2 more sources
Individual Radiosensitivity Assessment of the Families of Ataxia-Telangiectasia Patients by G2-Checkpoint Abrogation [PDF]
Sultan Qaboos University Medical Journal, 2019 Objectives: Ataxia-telangiectasia (A-T) is an autosomal recessive multisystem disorder characterised by cerebellar degeneration, telangiectasia, radiation sensitivity, immunodeficiency, oxidative stress and cancer susceptibility. Epidemiological research
Asghar Aghamohammadi +7 more
doaj +2 more sources
Predictive value of serum apolipoprotein panel (ApoA1 / ApoA2 / ApoA4) as a biomarker for individual radiosensitivity [PDF]
Lipids in Health and DiseaseBackground Significant interindividual variability in radiosensitivity poses a major challenge to conventional radiation protection and radiotherapy.
Na Huang +10 more
doaj +2 more sources
Telomere Length Dynamics and Chromosomal Instability for Predicting Individual Radiosensitivity and Risk via Machine Learning. [PDF]
J Pers Med, 2021 Luxton JJ +6 more
europepmc +2 more sources