Results 71 to 80 of about 155,608 (302)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Relaxation and breakup of an initially extended drop in an otherwise quiescent fluid [PDF]

open access: yes, 1989
In this paper we examine some general features of the time-dependent dynamics of drop deformation and breakup at low Reynolds numbers. The first aspect of our study is a detailed numerical investigation of the ‘end-pinching’ behaviour reported in a ...
Leal, L. G., Stone, H. A.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Similarity between the primary and secondary air-assisted liquid jet breakup mechanism

open access: yes, 2007
we report an ultrafast synchrotron x-ray phase contrast imaging study of the primary breakup mechanism of a coaxial air-assisted water jet. We demonstrate that there exist great similarities in the phenomenology of primary breakup with that of the ...
A. N. Kolmogorov   +4 more
core   +1 more source

Coulomb breakup effects on the optical potentials of weakly bound nuclei [PDF]

open access: yes, 2004
The optical potential of halo and weakly bound nuclei has a long range part due to the coupling to breakup that damps the elastic scattering angular distributions.
Al-Khalili   +58 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Evolution From Past to Future Conditions of Fast Ice Coverage in James Bay

open access: yesFrontiers in Earth Science, 2019
Fast ice is often used by coastal communities in the James Bay area for transportation in winter using snowmobiles. Therefore, the extent of fast ice along the James Bay coastline is important for land use and any changes to these extents may have ...
Wael Taha   +3 more
doaj   +1 more source

Coulomb and nuclear effects in breakup and reaction cross sections

open access: yes, 2016
We use a three-body Continuum Discretized Coupled Channel (CDCC) model to investigate Coulomb and nuclear effects in breakup and reaction cross sections.
Canto, L. Felipe   +2 more
core   +1 more source

Romantic Breakups, Heartbreak and Bereavement—Romantic Breakups

open access: yesPsychology, 2011
This literature review suggests that romantic breakups may lead to bereavement symptoms including intrusive thoughts and attempts to suppress them and insomnia as well as morbidity factors including broken heart syndrome and immune dysfunction. Although the broken heart syndrome has mimicked real heart attacks, angiograms revealed no clogged arteries ...
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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