Results 41 to 50 of about 3,052,066 (346)
Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
New England Journal of Medicine, 2021 Copyright © 2021 Massachusetts Medical Society. BACKGROUND Patients with metastatic triple-negative breast cancer have a poor prognosis. Sacituzumab govitecan is an antibody–drug conjugate composed of an antibody targeting the human trophoblast cell ...
A. Bardia +29 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
European Journal of Breast Health, 2016 Gestational gigantomastia is a rare condition characterized by fast, disproportionate and excessive breast growth, decreased quality of life in pregnancy, and presence of psychologic as well as physical complications. The etiology is not fully understood,
Halil Türkan +3 more
doaj +1 more source
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023 Granular cell tumor is very rarely seen in the breast. It is common in 30–50 years of age but can occur at any age. It simulates malignancy on clinical and radiological examination.
Charusheela Rajesh Gore +4 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Evaluating the Association between Breast Arterial Calcification and Carotid Plaque Formation
European Journal of Breast Health, 2015 Objective: We aimed to evaluate the association between breast arterial calcification (BAC) and carotid plaque formation.Materials and Methods: The study group comprised 47 consecutive BAC (+) women, whereas the control group comprised 33 BAC (–) women ...
Mehmet Yağtu
doaj +1 more source
Breast within a breast: a review of breast hamartomas
International Journal of Clinical Practice, 1990 SummaryA 22‐year‐old woman who presented with a large lump in the left breast, subsequently found to be a breast hamartoma, is described. A full review is given of this rare and unusual benign breast lesion, which is likely to be recognised increasingly with the advent of mammographic screening.
J A, Paraskevopoulos +2 more
openaire +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Five-Year Disease-Free Follow-Up of a Borderline Breast Phyllodes Tumor in a 15-year-old Patient
European Journal of Breast Health, 2015 Phyllodes tumors are large breast tumors representing only 1% of breast neoplasms and are rarely seen in young women. Histologically, phyllodes tumors are classified as benign, borderline, or malignant based on the characteristics of the stroma. Although
Sertaç Ata Güler +2 more
doaj +1 more source
Potential action of cardamom (Elettaria cardamomum) against triple-negative breast cancer
BLDE University Journal of Health Sciences, 2023 Triple-negative breast cancer (TNBC) has been known as havoc among females globally. It is a heterogeneous group of cancer encompassing many breast cancers basically distinct by the lack of estrogen receptor, progesterone receptor, and overextension of ...
Akash Samanta +4 more
doaj +1 more source