Results 91 to 100 of about 2,749,776 (308)
The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites [PDF]
, 2020 Sarah Libring, Aparna Shinde, Monica Chanda, Maryam Nuru, Heather Peshak George, Aya M. Saleh, Ammara Abdullah, Tamara L. Kinzer‐Ursem, Sarah Calve, Michael K. Wendt, Luis Solorio +10 moreopenalex +1 more sourceCelecoxib decreases prostaglandin E\u3csub\u3e2\u3c/sub\u3e concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer [PDF]
, 2006 Background
Celecoxib inhibits PGE2 production in cancerous tissue. We previously reported that PGE2 levels in nipple aspirate fluid (NAF) and plasma were not decreased in women at increased breast cancer risk who received celecoxib 200 mg twice daily ...Flynn, John T., Hewett, John E., Quin, Wenyi, Sauter, Edward R., Schlatter, Lisa +4 morecore +1 more sourceAssessment of the proliferative, apoptotic and cellular renovation indices of the human mammary epithelium during the follicular and luteal phases of the menstrual cycle [PDF]
, 2005 Introduction During the menstrual cycle, the mammary gland goes through sequential waves of proliferation and apoptosis. in mammary epithelial cells, hormonal and non-hormonal factors regulate apoptosis.A Aakvaag, A Gompel, AC Andres, AC Nazario, Afonso CP Nazário, AM Soto, AR Means, B Mulac-Jericevic, BA Flaxman, BS Katzenellenbogen, BS Katzenellenbogen, Carolina M Maier, CK Watts, CS Potten, CS Potten, DC Brown, DJ Allan, DJ Ferguson, DP McDonnell, Edmund C Baracat, F Feuerhake, G Ferrieres, Geraldo R Lima, H Fanger, HI Hassan, J Gerdes, JC Reed, JC Sabourin, JD Jacquemier, JE Fata, JJ Going, JL Wittliff, JM Hall, JN Izquierdo, JR Masters, JR Masters, JS Meyer, Luiz Gerk de Azevedo Quadros, Maria Alicia H Navarrete, MC Pike, ML Dell'Aquila, OW Petersen, PM Vogel, PN Mainwaring, R Bassler, R Israel, R Ramakrishnan, RB Clarke, RB Dickson, Roberto Falzoni, RT Greenlee, SE Bates, SR Wellings, T Scholzen, TA Longacre, TJ Anderson, TJ Anderson, TJ Anderson, V Kumar, W McGuire +59 morecore +2 more sourcesPYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu +13 morewiley +1 more sourceRedefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies
, 2022 Denise M. Wolf, Christina Yau, Julia Wulfkuhle, Lamorna Brown Swigart, Rosa I. Gallagher, Pei Rong Evelyn Lee, Zelos Zhu, Mark Jesus M. Magbanua, Rosalyn W. Sayaman, Nicholas O’Grady, Amrita Basu, Amy L. Delson, Jean Philippe Coppé, Ruixiao Lu, Jerome J. Braun, Smita Asare, Laura Sit, Jeffrey B. Matthews, Jane Perlmutter, Nola M. Hylton, Minetta C. Liu, Paula R. Pohlmann, W. Fraser Symmans, Hope S. Rugo, Claudine Isaacs, Angela DeMichele, Douglas Yee, Donald A. Berry, Lajos Pusztai, Emanuel F. Petricoin, Gillian L. Hirst, Laura J. Esserman, Laura van ‘t Veer +32 moreopenalex +1 more sourceAdjuvant chemotherapy and survival among patients 70 years of age and younger with node-negative breast cancer and the 21-gene recurrence score of 26-30 [PDF]
, 2019 BACKGROUND: The benefits of chemotherapy in node-negative, hormone receptor-positive, and human epidermal growth factor receptor 2 (HER2)-negative breast cancer patients with the 21-gene recurrence score (RS) of 18-30, particularly those with RS 26-30 ...Cho, Young Up, Colditz, Graham A, Han, Yunan, Kim, Seung Il, Liu, Ying, Park, Byeong-Woo, Park, Seho, Park, Yikyung, Peterson, Lindsay L, Toriola, Adetunji T +9 morecore +1 more sourcePatient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert +16 morewiley +1 more sourceGlycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala +18 morewiley +1 more sourceMolecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study
npj Breast CancerPregnancy-associated breast cancer (PABC), diagnosed during or shortly after pregnancy, is a challenging entity with an aggressive biology and poor prognosis.Regina Peña-Enríquez, Begoña Bermejo, Marina Pollán, Alejandra Díaz-Chacón, Yolanda Jerez Gilarranz, José J Ponce Lorenzo, Antonio Fernández Aramburo, Blanca Cantos Sánchez de Ibargüen, Ana Santaballa Bertrán, Elena Galve-Calvo, Álvaro Jiménez-Arranz, Yolanda Fernández, María Eva Pérez, Susana De La Cruz, Antonio Anton-Torres, Fernando Moreno, María Jesús Vidal-Losada, María Helena López-Ceballos, Isabel Blancas, María José Echarri, Raúl Rincón, Rosalía Caballero, Ángel Guerrero-Zotano, Silvia Guil-Luna, Juan de la Haba-Rodríguez +24 moredoaj +1 more source
