Results 91 to 100 of about 7,353,326 (373)

A comparative study of mitoxantrone hydrochloride injection and technetium-99 m for tracing axillary sentinel nodes in patients with breast cancer

open access: yesBMC Cancer
Purpose An earlier multicenter phase III study demonstrated the safety and efficacy of mitoxantrone hydrochloride injection for tracing (MHI) for detecting sentinel lymph nodes (SLNs) in breast cancer patients.
Dechuang Jiao   +9 more
doaj   +1 more source

Outcomes and risk of subsequent breast events in breast‐conserving surgery patients with BRCA1 and BRCA2 mutation

open access: yesCancer Medicine, 2020
Purpose Previous studies provide inconsistent interpretations of the effect of inherited genetic factors on the survival and prognosis of patients with breast cancer. The aim of this study was to examine the effect of germline BRCA1 and BRCA2 mutation on
Fugui Ye   +6 more
doaj   +1 more source

Breast Cancer in Pregnancy

open access: yesThe Breast Journal, 2010
Pregnancy-related breast cancer (PBC) is one of the most common malignancies during pregnancy (approx. one in 3,000 pregnancies); up to 3% of breast cancers are diagnosed in pregnancy. As maternal age at the time of pregnancy continues to increase as the incidence of breast cancer, the incidence of PBC is expected to increase.
ROVERA, FRANCESCA ANGELA   +7 more
openaire   +5 more sources

Self-Reported Chemicals Exposure, Beliefs About Disease Causation, and Risk of Breast Cancer in the Cape Cod Breast Cancer and Environment Study: A Case-Control Study [PDF]

open access: yes, 2010
BACKGROUND: Household cleaning and pesticide products may contribute to breast cancer because many contain endocrine disrupting chemicals or mammary gland carcinogens.
Aschengrau, Ann   +3 more
core   +4 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Wnt5a induces ROR1 to recruit cortactin to promote breast-cancer migration and metastasis. [PDF]

open access: yes, 2019
ROR1 is a conserved oncoembryonic surface protein expressed in breast cancer. Here we report that ROR1 associates with cortactin in primary breast-cancer cells or in MCF7 transfected to express ROR1.
Briggs, Steven P   +7 more
core   +1 more source

Mapping the Human Exposome to Uncover the Causes of Breast Cancer. [PDF]

open access: yes, 2019
Breast cancer is an important cause of morbidity and mortality for women, yet a significant proportion of variation in individual risk is unexplained. It is reasonable to infer that unexplained breast cancer risks are caused by a myriad of exposures and ...
Bessonneau, Vincent, Rudel, Ruthann A
core   +2 more sources

Circulating tumor cells, disease progression, and survival in metastatic breast cancer.

open access: yesNew England Journal of Medicine, 2004
BACKGROUND We tested the hypothesis that the level of circulating tumor cells can predict survival in metastatic breast cancer. METHODS In a prospective, multicenter study, we tested 177 patients with measurable metastatic breast cancer for levels of ...
M. Cristofanilli   +10 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Breast bruises and breast cancer [PDF]

open access: yesBreast Cancer Research, 2015
While recently examining one of the early classic works on breast cancer epidemiology—Janet E. Lane-Claypon’s 1926 report to the United Kingdom Ministry of Health [1]—and its 1931 US counterpart [2], I was struck by one item in the list of commonplace “antecedent conditions”: breast bruises, a not uncommon occurrence.
openaire   +4 more sources

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