Results 101 to 110 of about 2,472,817 (358)
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Archives of Breast Cancer, 2018 Background: Breast cancer is considered a chronic disease owing to the increases in survival rate. Thus, better body image and patient satisfaction with the surgery have become more important factors to be considered when choosing the surgical approach ...
Asiie Olfatbakhsh +5 more
doaj +1 more source
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
Active Learning for Breast Cancer Identification [PDF]
arXiv, 2018 Breast cancer is the second most common malignancy among women and has become a major public health problem in current society. Traditional breast cancer identification requires experienced pathologists to carefully read the breast slice, which is laborious and suffers from inter-observer variations.
arxiv
Unique Breast Cancer Features Within the Vietnamese Population
, 2017 BACKGROUND: Breast cancer is known to be a heterogeneous disease across women, and even within individual tumors. However, relatively little is known about heterogeneity across cultures.
Bondy, Melissa +2 more
core
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Review of studies in field of the effects of nanotechnology on breast cancer [PDF]
arXiv, 2018 Cancer is the main cause of mortality at the developed countries and is the second cause of mortality at the developing countries and breast cancer is the most prevalent malignancy and the first cause of mortality among women of the world. At the US, 28% of new cancer cases and 15% of mortality caused by that in 2010 was caused by breast cancer ...
arxiv
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
An Address ON THE IMPORTANCE OF EXPLORATORY INCISION IN CANCER OF THE BREAST [PDF]
, 1925 Duncan C. L. Fitzwilliams
openalex +1 more source