Results 21 to 30 of about 2,749,776 (308)

DGKZ promotes TGFβ signaling pathway and metastasis in triple-negative breast cancer by suppressing lipid raft-dependent endocytosis of TGFβR2

Cell Death and Disease, 2022
Diacylglycerol kinase ζ (DGKZ) is a diacylglycerol kinase that metabolizes diacylglycerol to yield phosphatidic acid, and its function in breast cancer progression remains unclear. In this study, via screening of a CRISPR-Cas9 knockout library containing
Yuanyuan Zhao, Hefen Sun, Xuan Li, Qiqi Liu, Yang Liu, Yifeng Hou, Wei Jin   +6 more
doaj   +1 more source

Premenopausal endogenous oestrogen levels and breast cancer risk: a meta-analysis. [PDF]

, 2011
BACKGROUND: Many of the established risk factors for breast cancer implicate circulating hormone levels in the aetiology of the disease. Increased levels of postmenopausal endogenous oestradiol (E2) have been found to increase the risk of breast cancer ...
AH Eliassen, C Frost, CR Rosenberg, D J Bratton, DJ Hand, DK Wysowski, EW Steyerberg, G Chene, HV Thomas, J Russo, JN Matthews, JP Costantino, JTCB Herjan, K Tanabe, K Walker, K Walker, KJ Helzlsouer, LJ Martin, M Kabuto, MC Pike, MH Gail, N Vasiljevic, R DerSimonian, R Kaaks, RC Travis, RF Galbraith, S Greenland, SA Missmer, The Endogenous Hormones and Breast cancer Collaborative Group, TJ Key   +29 more
core   +1 more source

Dyslipidemia is associated with a poor prognosis of breast cancer in patients receiving neoadjuvant chemotherapy

BMC Cancer, 2023
Background Lipid metabolism disorders may be involved in the occurrence and development of breast cancer. This study aimed to investigate the serum lipid changes during neoadjuvant chemotherapy for breast cancer and the effect of dyslipidemia on the ...
Youzhao Ma, Minhao Lv, Peng Yuan, Xiuchun Chen, Zhenzhen Liu   +4 more
doaj   +1 more source

Impact of breast cancer subtypes on 3-year survival among adolescent and young adult women. [PDF]

, 2013
IntroductionYoung women have poorer survival after breast cancer than do older women. It is unclear whether this survival difference relates to the unique distribution of hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2)-defined ...
Clarke, Christina A, DeRouen, Mindy C, Gomez, Scarlett L, Keegan, Theresa HM, Kurian, Allison W, Press, David J, Tao, Li   +6 more
core   +2 more sources

A case of giant cell tumor of the breast, clinically suspected as malignant breast tumor

Surgical Case Reports, 2019
Background Giant cell tumor (GCT) of the breast is scarce. We report a case of GCT of the breast which was suspected as a malignant breast tumor. Case presentation A 74-year-old woman noticed a tender lump in her right breast.
Mitsuo Terada, Naomi Gondo, Masataka Sawaki, Masaya Hattori, Akiyo Yoshimura, Haruru Kotani, Yayoi Adachi, Madoka Iwase, Ayumi Kataoka, Kayoko Sugino, Makiko Mori, Nanae Horisawa, Yuri Ozaki, Hiroji Iwata   +13 more
doaj   +1 more source

Amyloid tumor of the breast

Surgical Case Reports, 2019
Background Amyloid tumor of the breast is a rare disease, which was first reported in 1973. To date, only six cases have been reported in Japan. Case presentation A 45-year-old woman who had a medical history of Sjogren’s syndrome presented with a lump ...
Makiko Mori, Haruru Kotani, Masataka Sawaki, Masaya Hattori, Akiyo Yoshimura, Naomi Gondo, Yayoi Adachi, Ayumi Kataoka, Kayoko Sugino, Nanae Horisawa, Mitsuo Terada, Yuri Ozaki, Hiroji Iwata   +12 more
doaj   +1 more source

Conjoint analysis of circulating tumor cells and solid tumors for exploring potential prognostic markers and constructing a robust novel predictive signature for breast cancer

Cancer Cell International, 2021
Background Distance metastasis is the leading cause of death for breast cancer patients, and circulating tumor cells (CTCs) play a key role in cancer metastasis.
Xuan Li, Hefen Sun, Qiqi Liu, Yang Liu, Yifeng Hou, Wei Jin   +5 more
doaj   +1 more source

Breast Cancer Vaccine: Are We There Yet? [PDF]

, 2012
In lieu of an abstract, here is the article\u27s first paragraph: Breast cancer is the most fatal form of cancer for female population worldwide. National Cancer Institute (NCI) estimates 226,870 females and 2,190 males to be diagnosed with breast cancer
Chablani, Lipika
core   +2 more sources

Efficacy and safety of diphereline 11.25 mg, microrelin 11.25 mg, and microrelin 3.75 mg in premenopausal patients with breast cancer: a non-inferiority randomized clinical trial

BMC Cancer, 2023
Background Diphereline is a Gonadotropin-Releasing Hormone agonist commonly used in patients with breast cancer. This study aimed to compare the efficacy and safety of one-month and three-month Microrelin injections produced by Homa Pharmed Company with ...
Safa Najafi, Maryam Ansari, Zahra Omidi, Asiie Olfatbakhsh, Shiva Moghadam, Esmat-o-Sadat Hashemi, Niki Najafi, Shahpar Haghighat   +7 more
doaj   +1 more source

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression. [PDF]

, 2016
Molecular classification of cancers into subtypes has resulted in an advance in our understanding of tumour biology and treatment response across multiple tumour types. However, to date, cancer profiling has largely focused on protein-coding genes, which
Backofen, Rolf, Cao, Xuhong, Chinnaiyan, Arul M, Collins, Colin, Feng, Felix Y, Gawronski, Alexander, Han, Sumin, Hayes, Daniel F, Hosono, Yasuyuki, Iyer, Matthew K, Kregel, Steven, Ma, Teng, Malik, Rohit, Niknafs, Yashar S, Pierce, Lori J, Pitchiaya, Sethuramasundaram, Poliakov, Anton, Prensner, John R, Rae, James M, Sahinalp, Cenk S, Siebenaler, Ronald F, Singhal, Udit, Speers, Corey, Uhl, Michael, Wilder-Romans, Kari, Xiao, Lanbo, Zhang, Chao, Zhao, Shuang G   +27 more
core   +1 more source