Results 31 to 40 of about 4,221,746 (249)
GGNBP2 suppresses triple-negative breast cancer aggressiveness through inhibition of IL-6/STAT3 signaling activation
, 2018 Background
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, lacking effective targeted therapies, and whose underlying mechanisms are still unclear.Liu, Jingjing, Yang, Qianxi, Zhang, Jin, Hu, Yunhui, Zhao, Hui, Pan, Teng, Liu, Lei, Yagüe, Ernesto +7 morecore +1 more sourceAssociation of genetic variants at 8q24 with breast cancer risk. [PDF]
, 2008 Recent whole genome association studies of prostate, breast, and colorectal cancer have identified susceptibility loci on 8q24. We genotyped three variants associated with prostate cancer (rs10090154, rs13254738, and rs7000448), one associated with both ...Johnson, Nichola, Fletcher, Olivia, Coupland, Ben, dos Santos Silva, Isabel, Gibson, Lorna, Leonard, Angela, Fraser, Agnes, Ashworth, Alan, Houlston, Richard, Peto, Julian +9 morecore +1 more sourceEpigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan +4 morewiley +1 more sourceMissense variants in ATM in 26,101 breast cancer cases and 29,842 controls. [PDF]
, 2010 BACKGROUND: Truncating mutations in ATM have been shown to increase the risk of breast cancer but the effect of missense variants remains contentious.Schürmann, Peter, Olson, J.E., Seynaeve, C., Pita, Guillermo, Malcolm W.R. Reed, Beesley, Jonathan, Severi, G., Couch, Fergus J, Wang Gohrke, Shan, Jianjun Liu, Anton-Culver, H., Broeks, Annegien, Aittomaki, K., Kang, Daehee, Wang-Gohrke, Shan, Zachary Fredericksen, Hall, Katrine Blædel Pinholt, Kosma, V.M., Beckmann, Matthias W., Meindl, A., Heli Nevanlinna, Silva, Andreá Lema Da, Dunning, A.M., Morrison, J, Schmidt, Marjanka K., Keun-Young Yoo, van Leeuwen, F.E., Jenny Chang-Claude, Chang Claude, Jenny, Per Hall, Michael Bremer, Giles, Graham G., Georgia Chenevix-Trench, Fletcher, O, Noh, D.Y., Waltes, R., Silva, I. dos Santos, Brinton, L.A., Broeks, A., Bogdanova, Natalia V., Hopper, JL, Ekici, Arif B., Ashworth, Alan, Wang-Gohrke, S., Czene, Kamila, Smith, L (Letitia), Johnson, N., Orr, Nick, Spurdle, Amanda B., Van't Veer, L.J., Brinton, Louise A., Louise A. Brinton, Schurmann, P, Spurdle, AB, Flyger, Henrik, Melissa C. Southey, Kataja, V, Nordestgaard, Børge G., Douglas F. Easton, Veli-Matti Kosma, Kristiina Aittomäki, Liu, Jianjun, Elliott, Graeme, Ahmed, S., Zalutsky, Iosif V., Morrison, Jonathan, Pharoah, P.D., Bojesen, S.E., Breast Cancer Association Consortium, Lindblom, A., Platte, R., Platte, Radka, Spurdle, Amanda B, Kang, D., Pita, G., Johnson, N, Garcia-Closas, M., Olson, Janet E, Ko, Yon-Dschun, Nordestgaard, B.G., Antonenkova, N.N., Isabel dos Santos Silva, Fredericksen, Z, Milne, R.L., Laura Baglietto, Hopper, J.L., Cox, A, Manjeet K. Humphreys, García Closas, Montserrat, Nichola Johnson, Wang-Gohrke, S, Bojesen, Stig E., Dork, T., Milne, Roger L, Pharoah, P.D.P., Brauch, H, Brinton, LA, Reed, M.W.R., Humphreys, Manjeet K, Pita, G, Cox, Angela, Liu, J.J., Brock, I, AOCS Grp, Anton-Culver, H, Elliott, George Arthur, Olivia Fletcher, Ekici, Arif B, Marjanka K. Schmidt, Claus R. Bartram, Ian Brock, Jonathan Beesley, Bremer Michael, Peto, Julian, Johnson, Nichola, Dallas R. English, Giles, GG, Easton, Douglas F, Ashworth, A., Børge G. Nordestgaard, Alison M. Dunning, Radka Platte, Chenevix-Trench, G, Hall, Per, Lindblom, Annika, Annika Lindblom, Schurmann, P., Asperen, C.J. van, Ko, YD, GENICA Consortium, Baglietto, L, Humphreys, Manjeet K., Peter Devilee, Baglietto, Laura, Morrison, Ann Judith, Couch, FJ, Fasching, PA, Brinton, Louise A, English, Dallas R., Meindl, A, Severi, G, Brauch, H., Reed, Malcolm W. R., Nevanlinna, Heli, Burwinkel, B., Dong Young Noh, Jonathan Morrison, Reed, M.W., Bojesen, SE, John L. Hopper, Devilee, Peter, Orr, N, Javier Benítez, Hoda Anton-Culver, Lissowska, J, Tollenaar, Rob A E M, Bartram, CR, Giles, Graham G, Noh, DY, Schmidt, Marjanka K, Southey, Melissa C., Fredericksen, Z., Milne, RL, Beckmann, MW, Beesley, J, Yoo, Keun-Young, Blomqvist, Carl, Chanock, S., Milne, Roger L., Easton, Douglas F., Tuomas Heikkinen, Couch, Fergus J., Alan Ashworth, Schmidt, M.K., Benítez, Javier, Montserrat García-Closas, Wang, X.S., Giles, G.G., Fasching, Peter A., Barbara Burwinkel, Benitez, J, Schmutzler, RK, Dörk, Thilo, Peto, J., Couch, F.J., Angela Cox, Dunning, Alison M., Arif B. Ekici, Olson, Janet E., Kamila Czene, dos Santos Silva, Isabel, Mannermaa, A., Pharoah, Paul D. P., Stig E. Bojesen, Larsen, Marie Sofie Yoo, AOCS Group, Hiltrud Brauch, Blomqvist, C, Hamann, U., Chang-Claude, J., Tollenaar, Rob A. E. M., Vesa Kataja, Baglietto, L., Chenevix Trench, Georgia, Ahmed, Shahana, Veer, L.J. van 't, Wang, X., Strick, Reiner, Aittomaki, K, Strick, R, Bremer, M, Spurdle, A.B., Natalia V. Bogdanova, Margolin, Sara, Brock, I., Anton Culver, Hoda, Hopper, John L., Benitez, J., Hall, P, Waltes, Regina, Hamann, U, Zalutsky, Iosif V, Flora E. van Leeuwen, Anton-Culver, Hoda, Bogdanova, N.V., Antonenkova, NN, van Asperen, Christie J., Arias, J.I., Liu, J., Natalia N. Antonenkova, Henrik Flyger, Wang, XS, Wang, Xianshu, Liu, JJ, van Leeuwen, Flora E., Keith Humphreys, Yon-Dschun Ko, Morrison, J., Gaubert, Giles, Tollenaar, R.A., Janet E. Olson, Silva, Isabel dos Santos, Kataja, Vesa, Beckmann, Matthias W, Fasching, P.A., van Asperen, CJ, Ekici, A.B., Breast Canc Assoc Consortium, Ziogas, A, van Asperen, Christie J, Ziogas, Argyrios, Rita K. Schmutzler, Lissowska, J., Dunning, Alison M, Heikkinen, T., van 't Veer, L.J., Dunning, AM, Burwinkel, B, Czene, K, Broeks, A, Easton, DF, Tollenaar, Rob AEM, Tollenaar, RAEM, Kang, D, Zalutsky, IV, Hamann, Ute, Kosma, Veli-Matti, Dork,Thilo, Orr, N., English, D.R., Van't Veer, Laura J., Bogdanova, Natalia V, Chenevix-Trench, Georgia, Jolanta Lissowska, Humphreys, MK, Pharoah, Paul DP, Southey, M.C., Chang-Claude, J, Heikkinen, T, Sara Margolin, Ute Hamann, Rob A.E.M. Tollenaar, Smith, Letitia, Olson, JE, Annegien Broeks, Reed, MWR, Caroline Seynaeve, Leeuwen, F.E. van, Bremer, M., Roger L. Milne, Thilo Dörk, van Leeuwen, Flora E, Carl Blomqvist, Hall, P., Reed, Malcolm W R, Laura J. Van't Veer, Humphreys, K., Ziogas, A., Bojesen, Stig E, Schmutzler, R.K., Melanie Maranian, Ekici, AB, Iosif V. Zalutsky, Peto, J, Brauch, Hiltrud, Reed, Malcolm WR, Elliott, G., Amanda B. Spurdle, Chanock, Stephen, Julian Peto, Yoo, KY, Ignacio Arias, José, Bartram, Claus R., Smith, L., Beesley, J., Christie J. van Asperen, Beckmann, M.W., Daehee Kang, Argyrios Ziogas, van Leeuwen, FE, Strick, R., Yoo, K.Y., Arias, JI, Graeme Elliott, Devilee, P, Arias, José Ignacio, José Ignacio Arias, Ashworth, A, Hopper, John L, Nordestgaard, BG, Stephen Chanock, Lindblom, A, Meindl, Alfons, Bogdanova, NV, Hansen, Anne Lindblom, Arto Mannermaa, Humphreys, K, Margolin, S., Heikkinen, Tuomas, Ko, Yon Dschun, García-Closas, Montserrat, Fletcher, O., Flyger, H., Travis, Brandon Reed, Southey, MC, Aittomäki, Kristiina, Zalutsky, I.V., Reiner Strick, Elliott, G, Waltes, R, Nevanlinna, H., Fergus J. Couch, Schmutzler, Rita K., Orr, Nick; id_orcid, Nick Orr, English, Dallas R, van 't Veer, LJ (Laura), Guillermo Pita, Severi, Gianluca, English, DR, Yoo, Keun Young, Kosma, VM, Garcia-Closas, M, Pharoah, Paul D P, Seynaeve, Caroline, Shan Wang-Gohrke, Van't Veer, Laura J, Graham G. Giles, dos Santos Silva, I., Devilee, P., Nordestgaard, Børge G, Antonenkova, Natalia N., Peter A. Fasching, Czene, K., Paul D.P. Pharoah, Bremer, Michael, Platte, R, Maranian, Melanie, Silva, ID, Chanock, S, Maranian, M., Fletcher, Olivia, Shahana Ahmed, Burwinkel, Barbara, Humphreys, M.K., Southey, Melissa C, Pharoah, PDP, Antonenkova, Natalia N, Flyger, H, Margolin, S, Matthias W. Beckmann, Alfons Meindl, Mannermaa, A, Schmutzler, Rita K, Noh, Dong Young, Tollenaar, R.A.E.M., Dork, T, Cox, A., Nevanlinna, H, Bartram, Claus R, van Asperen, C.J., Kosma, Veli Matti, Ahmed, S (Shahana), Mannermaa, Arto, Easton, D.F., Chang-Claude, Jenny, Lissowska, Jolanta, Peter Schürmann, Ko, Y.D., Xianshu Wang, Brock, Ian, Silva, I.D., Chenevix-Trench, G., Kataja, V., Maranian, M, Humphreys, Keith, Fasching, Peter A, Regina Waltes, Fredericksen, Zachary, Gianluca Severi, Blomqvist, C., Letitia Smith, Bartram, C.R., kConFab Investigators, Silva, IDS, Fletcher, O;Johnson, N;Dos Santos Silva, I;Orr, N;Ashworth, A;Nevanlinna, H;Heikkinen, T;Aittomäki, K;Blomqvist, C;Burwinkel, B;Bartram, CR;Meindl, A;Schmutzler, RK;Cox, A;Brock, I;Elliott, G;Reed, MW;Southey, MC;Smith, L;Spurdle, AB;Hopper, JL;Couch, FJ;Olson, JE;Wang, X;Fredericksen, Z;Schürmann, P;Waltes, R;Bremer, M;Dörk, T;Devilee, P;van Asperen, CJ;Tollenaar, RA;Seynaeve, C;Hall, P;Czene, K;Humphreys, K;Liu, J;Ahmed, S;Dunning, AM;Maranian, M;Pharoah, PD;Chenevix-Trench, G;Beesley, J;Bogdanova, NV;Antonenkova, NN;Zalutsky, IV;Anton-Culver, H;Ziogas, A;Brauch, H;Ko, YD;Hamann, U;Fasching, PA;Strick, R;Ekici, AB;Beckmann, MW;Giles, GG;Severi, G;Baglietto, L;English, DR;Milne, RL;Benitez, J;Arias, JI;Pita, G;Nordestgaard, BG;Bojesen, SE;Flyger, H;Kang, D;Yoo, KY;Noh, DY;Mannermaa, A;Kataja, V;Kosma, VM;Garcia-Closas, M;Chanock, S;Lissowska, J;Brinton, LA;Chang-Claude, J;Wang-Gohrke, S;Broeks, A;Schmidt, MK;van Leeuwen, FE;Van't Veer, LJ;Margolin, S;Lindblom, A;Humphreys, MK;Morrison, J;Platte, R;Easton, DF +425 morecore +1 more sourceLigand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada +5 morewiley +1 more sourceAmyloid tumor of the breast
Surgical Case Reports, 2019 Background Amyloid tumor of the breast is a rare disease, which was first reported in 1973. To date, only six cases have been reported in Japan. Case presentation A 45-year-old woman who had a medical history of Sjogren’s syndrome presented with a lump ...Makiko Mori, Haruru Kotani, Masataka Sawaki, Masaya Hattori, Akiyo Yoshimura, Naomi Gondo, Yayoi Adachi, Ayumi Kataoka, Kayoko Sugino, Nanae Horisawa, Mitsuo Terada, Yuri Ozaki, Hiroji Iwata +12 moredoaj +1 more sourceAusencia de la mutación BRCA1 del (exones 9-12) en familias con cáncer de seno / ovario fuera de hispanos mexicanos [PDF]
, 2009 3 páginasThe frequency and spectrum of germ line mutations in the
high-penetrance breast cancer susceptibility genes BRCA1
and BRCA2 shows considerable variation by ethnic group.Seidel Renkert, Antje, Colombian Breast Cancer Study Group (COLBCS), Torres, Diana, Seidel-Renkert, Antje, Rashid, Muhammad U., Briceño Balcázar, Ignacio, Weitzel, Jeffrey N., Hamann, Ute, Briceno, Ignacio +8 morecore +1 more source
