Results 31 to 40 of about 7,353,326 (373)

Identification of signaling pathways in early mammary gland development by mouse genetics [PDF]

open access: yes, 2004
The mammary gland develops as an appendage of the ectoderm. The prenatal stage of mammary development is hormone independent and is regulated by sequential and reciprocal signaling between the epithelium and the mesenchyme.
A Yang   +20 more
core   +2 more sources

Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND Genetic testing for breast cancer susceptibility is widely used, but for many genes, evidence of an association with breast cancer is weak, underlying risk estimates are imprecise, and reliable subtype-specific risk estimates are lacking ...
L. Dorling   +196 more
semanticscholar   +1 more source

Expert consensus on clinical applications of ovarian function suppression for Chinese women with early breast cancer (2024 edition) [PDF]

open access: yesZhongguo aizheng zazhi
In China, 60% of breast cancer patients were premenopausal women at the time of diagnosis. Compared with postmenopausal women, premenopausal women have strong ovarian function and secrete estrogen to promote breast cancer growth.
Committee of Breast Cancer Society, China Anti-Cancer Association
doaj   +1 more source

Overdiagnosis and overtreatment of breast cancer: Overdiagnosis in randomised controlled trials of breast cancer screening [PDF]

open access: yes, 2005
Data from randomised controlled trials of mammographic screening can be used to determine the extent of any overdiagnosis, as soon as either a time equivalent to the lead-time has elapsed after the final screen, or the control arm has been offered ...
AB Miller   +18 more
core   +3 more sources

Neoadjuvant camrelizumab plus nab-paclitaxel and epirubicin in early triple-negative breast cancer: a single-arm phase II trial

open access: yesNature Communications, 2023
Immunotherapy combined with chemotherapy has been demonstrated to be effective in early triple-negative breast cancer (TNBC). In this single-arm, phase II study with Simon’s two-stage design, we investigated the efficacy and safety of neoadjuvant ...
Chengzheng Wang   +11 more
doaj   +1 more source

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

open access: yes, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Breast cancer statistics, 2019

open access: yesCa, 2019
This article is the American Cancer Society’s biennial update on female breast cancer statistics in the United States, including data on incidence, mortality, survival, and screening.
C. DeSantis   +7 more
semanticscholar   +1 more source

DGKZ promotes TGFβ signaling pathway and metastasis in triple-negative breast cancer by suppressing lipid raft-dependent endocytosis of TGFβR2

open access: yesCell Death and Disease, 2022
Diacylglycerol kinase ζ (DGKZ) is a diacylglycerol kinase that metabolizes diacylglycerol to yield phosphatidic acid, and its function in breast cancer progression remains unclear. In this study, via screening of a CRISPR-Cas9 knockout library containing
Yuanyuan Zhao   +6 more
doaj   +1 more source

Exploring factors contributing to low uptake of the NHS Breast Cancer Screening Programme among Black African women in the UK [PDF]

open access: yes, 2017
Breast cancer is the most common cancer among women in the United Kingdom (UK) accounting for about 15% of cancer deaths. The National Breast Cancer Screening Programme in the UK was introduced in 1988 to assist with early detection and better management
Ali, Nasreen   +3 more
core   +1 more source

Breast tumor diagnosis in digital mammograms [PDF]

open access: yes, 2019
Breast cancer has been classified as the most common cancer in most part of the world [1]. Breast cancer is caused by the growth of the abnormal cells in the breast. Breast cancer not only develops in women but also on men.
Gaik Tay, Kim   +2 more
core   +1 more source

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