Results 61 to 70 of about 2,666,341 (347)

Cross-talk of four types of RNA modification proteins with adenosine reveals the landscape of multivariate prognostic patterns in breast cancer

Frontiers in Genetics, 2022
Background: Breast cancer (BC) is the most common malignant tumour, and its heterogeneity is one of its major characteristics. N6-methyladenosine (m6A), N1-methyladenosine (m1A), alternative polyadenylation (APA), and adenosine-to-inosine (A-to-I) RNA ...
Xuliren Wang, Fangdie Ye, Min Xiong, Bingqiu Xiu, Weiru Chi, Qi Zhang, Jingyan Xue, Ming Chen, Liyi Zhang, Jiong Wu, Jiong Wu, Yayun Chi   +11 more
doaj   +1 more source

Communicating biopsy results from breast screening assessment::current practice in English breast screening centres and staff perspectives of telephoning results [PDF]

, 2019
Objective To record how breast screening centres in England deliver all biopsy results (cancer/non-cancer) from the breast assessment visit.Design Online survey of 63 of 79 breast screening centres in England from all regions (East Midlands, East of ...
Casey, Margaret, Ellard, David, Jenkins, Jacquie, Johnson, Rebecca, Kearins, Olive, Sandhu, Harbinder, Taylor Phillips, Sian, Williamson, Sian   +7 more
core   +2 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Breast Cancer

South African Medical Journal, 2014
The management of breast cancer requires a multidisciplinary approach in its broadest sense. In keeping with this ethos, the May edition of CME contains articles written by surgeons, oncologists, epidemiologists, nurses, physiotherapists, occupational therapists and patient advocates.
Rottmann, Nina, Ewertz, Marianne, Hansen, Dorte Gilså   +2 more
openaire   +8 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Guideline for the Management Pathway and Quality Control of Breast Cancer Prevention and Treatment in China's Counties

Cancer Innovation
Breast cancer is one of the most common malignant tumors among women in China, with approximately 306,000 new cases reported in 2016. Notably, around 33% (100,400) of these cases occurred in rural areas.
Breast Cancer Expert Committee of National Cancer Quality Control Center, Cancer Prevention and Treatment Committee of Healthy China Research Center   +1 more
doaj   +1 more source

A case of radiation-associated angiosarcoma after breast cancer

Surgical Case Reports, 2018
Background Radiation-associated angiosarcoma (RAAS) is a rare subtype of secondary angiosarcoma that is characterized by rapid proliferation and extensive tissue infiltration.
Nanae Horisawa, Yayoi Adachi, Masataka Sawaki, Masaya Hattori, Akiyo Yoshimura, Naomi Gondo, Haruru Kotani, Ayumi Kataoka, Kayoko Sugino, Makiko Mori, Mitsuo Terada, Yuri Ozaki, Hiroji Iwata   +12 more
doaj   +1 more source

Diagnostic diversity and heterogeneity of tumors: a real-world study of metastasis re-biopsy in advanced breast cancer

Chinese Medical Journal, 2022
. Background:. Re-biopsy of metastasis in advanced breast cancer (ABC) has become an international convention to assist the diagnosis and evaluation of tumor heterogeneity.
Huimin Lv, Limin Niu, Mengwei Zhang, Huiai Zeng, Shengnan Zhao, Min Yan, Yanjie Yin, Xiuyuan Hao   +7 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Tumor-specific MHC-II guides anthracycline exemption and immunotherapy benefit in breast cancer

Biomarker Research
Background Anthracycline-based chemotherapy, while foundational in breast cancer treatment, confers substantial cardiotoxicity. Identifying biomarkers to guide anthracycline exemption without compromising efficacy has remained an unresolved clinical ...
Zehao Wang, Yanhui Wang, Zhishuang Gao, Yue Zhou, Xiaoting Chen, Rui Xu, Yangsiyuan Zhao, Yi Zhang, Bingqiu Xiu, Jing Liu, Zhiming Shao, Shengmei Gu, Jingyan Xue, Jiong Wu   +13 more
doaj   +1 more source