Results 191 to 200 of about 9,188,168 (301)

A Deep Learning Model Incorporating Spatiotemporal Asymmetries on Longitudinal Mammograms to Predict Breast Cancer Risk. [PDF]

Radiol Artif Intell
Zhou Z, Arefan D, Zuley ML, Sumkin JH, Wu S.   +4 more
europepmc   +1 more source

Breast Cancer Tissue Bank Blood Samples

This BCTB subcollection consists of blood samples taken from breast cancer patients and others. It is further broken down into a number of blood components.

core  

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Blood DNA methylation and breast cancer risk: a prospective nested case-control study. [PDF]

EBioMedicine
Rodriguez J, Grassmann F, Kaukonen D, Hägg S, Humphreys K, Eriksson M, Zhang Y, Morawitz K, Gabrielson M, Hall P, Czene K.   +10 more
europepmc   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian, Teizo Yoshimura, Kun Zhao, Chunning Li, Tong Gao, Ziyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Akihiro Matsukawa   +8 more
wiley   +1 more source

Assisted Reproductive Technologies (ART) and breast cancer risk: hormonal treatments under the spotlight. [PDF]

Breast Cancer Res Treat
Boldrini C, Bottalico M, Lia FL, Longo V, Gigli S.   +4 more
europepmc   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

WDCN: a comprehensive neural network based approach for estimating breast cancer risk. [PDF]

Brief Bioinform
Xu H, Zhang G, Lin H, Grosser M, Lu J.
europepmc   +1 more source

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

Advanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian, Jiasha Wu, Fusheng Xu, Yan Zuo, Huaxing Shen, Rui Ji, Luyi Wang, Na Li, Yanting Sun, Yongsheng Yu, Yejiao Shi, Honggang Hu, Feng Xu, Dan Huang, Xiaochun Hu   +14 more
wiley   +1 more source

Exploring Traditional Breast Cancer Risk Genes Among Aboriginal and Torres Strait Islander Women. [PDF]

Life (Basel)
Meehan K, Pilkington L, Khan A, Pachter N, Spalding L, Milligan Armstrong A, Redfern C, Redfern A.   +7 more
europepmc   +1 more source