Results 111 to 120 of about 584,073 (346)
Discount rates and the education gradient in mammography in the uk [PDF]
, 2013 I analyse intertemporal decisions on undertaking breast cancer screening by women aged 50-64years in the UK and provide estimates of the rate of discounting potential future benefits of screening.
Crossley +25 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Indian Journal of Community MedicineBackground: Breast cancer, the most common malignancy among women globally, recorded over 2.26 million new cases and almost 685,000 deaths in the same year.
V Divya, Uma R Maheshwari, V Damodaran
doaj +1 more source
Knowledge and Practice of Breast Self-Examination among Women in Seberang Perai Utara District, Penang: AMDI Medical Coach Experience [PDF]
, 2015 Breast cancer is the leading cause of cancer mortality in women and is a major health concern in both developing and developed countries 1. Regular breast cancer screening is the single most important public health strategy to reduce breast cancer ...
A. Karim, Noor Khairiah +4 more
core
Screening for breast cancer [PDF]
BMJ, 1993 The feasibility of mass population screening for breast cancer by clinical examination and x-ray mammography was studied. The results indicate that such a programme could be conducted effectively by non-medical staff and be safe from the dangers of irradiation.
openaire +3 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Indian Journal of Community MedicineBackground: Breast cancer (BC) is the leading cancer in India among women accounting for 13.5% of all cancer cases. One of the leading causes of high breast cancer deaths is poor awareness about risk factors, symptoms and screening leading to the late ...
G Vinothkumar, V Saravanan, V Dorthy
doaj +1 more source
Compare Breast Cancer Screening, Diagnosis, and Treatment Between Medicare Patients With and Without ADRD [PDF]
, 2020 Xingran Weng +4 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source