Results 71 to 80 of about 584,073 (346)

Abbreviated MRI Screening in Turkish Women Aged 40–69 With Dense Breasts: A Prospective Feasibility Study

Technology in Cancer Research & Treatment
Introduction We aimed to investigate the feasibility of abbreviated protocol (AP) breast magnetic resonance imaging (MRI) screening in women with dense breasts in a screening program in a middle-income country. Methods This prospective study included 649
Inci Kizildag Yirgin MD, Neslihan Cabioglu MD, Memduh Dursun MD, Omur Can Tasci MD, Aziz Şener MD, Gulcin Vatandaş MS, Gonul Aykuter MD, Ravza Yilmaz MD, Ayse Nilufer Ozaydin MD, Sibel Ozkan Gurdal MD, Beyza Ozcinar MD, Nuran Akyurt MS, Vahit Ozmen MD, Arda Kayhan MD, Erkin Aribal MD   +14 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

BREAST CANCER SCREENING KNOWLEDGE AND PRACTICE AMONG WOMEN IN SOUTHEAST OF IRAN [PDF]

Acta Medica Iranica, 2008
Breast cancer is the most common cancer occurring among women. The mortality rate of breast cancer can be reduced by regular breast cancer screening program.
Z Heidari, H. R Mahmoudzadeh-Sagheb, N Sakhavar   +2 more
doaj   +1 more source

Identifying the Link Between Chemical Exposures and Breast Cancer in African American Women via ToxCast High Throughput Screening Data [PDF]

, 2021
Katelyn M. Polemi, Vy Kim Nguyen, Julien Heidt, Adam Kahana, Olivier Jolliet, Justin A. Colacino   +5 more
openalex   +1 more source

Overdiagnosis due to screening mammography for women aged 40 years and over [PDF]

, 2018
This is a protocol for a Cochrane Review. The objective was to assess the effect of screening mammography for breast cancer on overdiagnosis in women aged 40 years and older at average risk of breast ...
Barratt, Alexandra, Bell, Katy, Glasziou, Paul P., Houssami, Nehmat, Jacklyn, Gemma, Mcgeechan, Kevin   +5 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Mammographic density and breast cancer risk in breast screening assessment cases and women with a family history of breast cancer. [PDF]

, 2017
BACKGROUND: Mammographic density has been shown to be a strong independent predictor of breast cancer and a causative factor in reducing the sensitivity of mammography.
Allgood, Prue C, Astley, Susan M, Black, Richard, Cooke, Julie, Dobson, Hilary M, Duffy, Stephen W, Duncan, Karen A, Gilbert, Fiona J, Gillan, Maureen GC, Lim, Yit Y, Maroni, Roberta, Michell, Michael J, Morrish, Oliver WE, Purushothaman, Hema N, Suaris, Tamara, Tucker, Lorraine, Willsher, Paula, Young, Kenneth C   +17 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The Relationship between Risk Levels of Breast Cancer and Use of Early Diagnosis and Screening Services in Healthcare Workers in Turkey

Iranian Journal of Public Health, 2020
Background: This study aimed to determine the factors affecting early diagnosis and screening behaviors of healthcare workers concerning breast cancer and the breast cancer risk levels using the risk identification model and to evaluate the relationship ...
Ayla ACIKGOZ, Selda YORUK, Hulya TURKMEN, Gul ERGOR   +3 more
doaj   +1 more source