Results 61 to 70 of about 5,162,410 (252)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Women’s satisfaction of the Maltese breast screening programme : a cross-sectional survey [PDF]

, 2015
Introduction: Breast cancer is the most common form of cancer among women,1 with 425,000 new cases diagnosed in Europe each year.2 The latter posed a detrimental health problem for years in Malta and consequently, a National Breast Screening ...
Marmarà, Vincent-Anthony, Marmara, Vincent, Curtis, Judi, Marmara, Danika   +3 more
core  

Sexuality as an aspect of nursing care for women receiving chemotherapy for breast cancer in an Irish context [PDF]

, 2005
In this article, findings are presented from a study that aimed to explore the perceptions and experiences of a sample of nurses in addressing sexuality as an aspect of care for women receiving chemotherapy for breast cancer.
Hyde, Abbey, Lavin, Marie, Abbey Hyde, Marie Lavin   +3 more
core   +1 more source

Identification of cell adhesion-related subtypes and construction of risk model to predict breast cancer prognostic and immunological properties

World Journal of Surgical Oncology
Background Breast invasive carcinoma is the most common form of breast cancer, often resulting in recurrence or metastasis in patients. Cell adhesion molecules play a crucial role in modulating the interactions between tumor cells and surrounding cells ...
De-Ming Lv, Li Yang, Chen Fan, Ling-Hui Fang, Su-Fen Cheng   +4 more
doaj   +1 more source

First Intraoperative Radiation Therapy Center in Africa: First 2 Years in Operation, Including COVID-19 Experiences

JCO Global Oncology, 2020
PURPOSEThere is a shortage of radiation therapy service centers in low- to middle-income countries. TARGIT–intraoperative radiation therapy (IORT) may offer a viable alternative to improve radiation treatment efficiency and alleviate hospital patient ...
Yastira Ramdas, Carol-Ann Benn, Michelle van Heerden   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Association of CA12 with calcification in ER+/HER-2 negative breast cancer

Discover Oncology
Background Calcification in breast cancer is closely associated with ER+/HER2- breast cancer, and identifying key molecular markers is crucial for early diagnosis and treatment.
Yuxuan Zhu, Qin Du, Yiyang Ma, Nanxin Xu, Yuhang Luo, Di Liu   +5 more
doaj   +1 more source

Does Gross Margin Examination Reduce Re-excision Rate in Breast Conservation for Invasive Carcinoma? CALLER Review

European Journal of Breast Health, 2020
Objective: Determine if Gross Margin Examination reduces margin re-excision rate. Our institutional practice is to perform Gross Margin Examination (GME) with Real-time re-excision (RRE) for all breast conservation specimens with Invasive Carcinoma ...
Suzanne Hoekstra, Diane Stoller, Haya Raef   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Prognostic prediction for inflammatory breast cancer patients using random survival forest modeling

Translational Oncology
Background: Inflammatory breast cancer (IBC) is an aggressive and rare phenotype of breast cancer, which has a poor prognosis. Thus, it is necessary to establish a novel predictive model of high accuracy for the prognosis of IBC patients.
Yiwei Jia, Chaofan Li, Cong Feng, Shiyu Sun, Yifan Cai, Peizhuo Yao, Xinyu Wei, Zeyao Feng, Yanbin Liu, Wei Lv, Huizi Wu, Fei Wu, Lu Zhang, Shuqun Zhang, Xingcong Ma   +14 more
doaj   +1 more source