Results 51 to 60 of about 2,128,083 (311)

Breast conservation and oncoplastic surgery are associated with improved quality of life

Frontiers in Oncology
IntroductionLocal treatment can be distressful to breast cancer patients. We aimed to evaluate how different types of local treatment impact the quality of life of patients.MethodsIn this retrospective cohort study, one-year postoperative Breast-Q ...
Daniel Barbalho, Natalia Polidorio, Lincon Mori, Alfredo Barros, Marcelo Sampaio, Sandro Melo, Amilcar Assis, Pamela Bioni, Giovanna Miziara, Murilo Fraga, Felipe Andrade   +10 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Breast conservation Surgery for Carcinoma Breast

Annals of King Edward Medical University, 2016
A prospective study consisting of 15 patients with proven carcinoma of breast was carried out on the surgical floor of Sir Ganga Ram Hospital , Lahore from December 2001 to May 2003. All the patients included in the study had either carcinoma in situ, or on clinical examination had T1N0M0, T1N1M0 or T2N0M0 tumour.
Aamer Zaman Khan, Basma Khan, Syed Asghar Naqi, Aftab Ahmad Ranjha, Khalid Javed Abid   +4 more
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Value of intra-operative ultrasound in localization of palpable or non-palpable breast tumors during breast conserving surgery

The Egyptian Journal of Radiology and Nuclear Medicine, 2018
Purpose: Our study was designed to assess the role of intra-operative ultrasound (IOUS) as a method of localization of palpable or non-palpable breast tumors during breast conserving surgery (BCS) and ensuring adequate margins by comparing pathological ...
Shorouk Zaky Abdel Aziz Abdelshafy, Medhat Mohamed Refaat, Gamal Elsayed Saleh, Mohammed I. Yousef   +3 more
doaj   +1 more source

Recurrence after breast conserving surgery; can re-excision with intraoperative margin assessment normalize the risk of local recurrence? [PDF]

Ain-Shams Journal of Surgery, 2009
Background: Breast conserving therapy (BCT), including breast conserving surgery (BCS) and radiotherapy has become the preferred method of treatment for early stage breast cancer.
Ayman M S Soliman, Yasser Abdel Reheem, Osama M El-Shiekh, Ahmed M Awad Ellakany, Hala Rashad   +4 more
doaj   +1 more source

A new indication and surgical procedure to reduce fat necrosis after breast-conserving surgery using an inframammary adipofascial flap

Asian Journal of Surgery, 2022
Background: There is little information on the risk factors for fat necrosis after breast-conserving surgery using an inframammary adipofascial flap (IAF).
Miyuko Yoshikawa, Makoto Ishitobi, Saori Matsuda, Mao Kimoto, Chihiro Higashi, Nao Imai, Aya Noro, Masako Yamashita, Noriko Hanamura, Tomoko Ogawa   +9 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Ultrasound-guided breast-sparing surgery to improve cosmetic outcomes and quality of life. A prospective multicentre randomised controlled clinical trial comparing ultrasound-guided surgery to traditional palpation-guided surgery (COBALT trial)

BMC Surgery, 2011
Background Breast-conserving surgery for breast cancer was developed as a method to preserve healthy breast tissue, thereby improving cosmetic outcomes.
Bergers Elisabeth, Taets van Amerongen Annette HM, Bosch Anne, de Roos Wilfred K, de Widt Louise, Poortman Pieter, Muller Sandra, van der Veen Henk, Rijna Herman, Lopes Cardozo Alexander MF, Schreurs Hermien WH, Zonderhuis Barbara M, Krekel Nicole MA, van der Linden Mecheline HM, de Lange de Klerk Elly SM, Winters Henri AH, Meijer Sybren, van den Tol Petrousjka MP   +17 more
doaj   +1 more source

Breast-conserving surgery using an inframammary fold incision technique for breast cancer

, 2017
Breast-conserving surgery is an established alternative for the majority of women with early stage breast cancer. Consensus on negative margins (no ink on tumour) for invasive cancer makes mutilating extensive lumpectomies unnecessary.
Sahlin, Christina, Hallberg, Håkan, Olofsson Bagge, Roger,, Heiman, Jenny,   +3 more
core   +1 more source