Results 51 to 60 of about 2,742,191 (376)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Anthropometry and body composition of 18 year old men according to duration of breast feeding: birth cohort study from Brazil [PDF]

open access: yes, 2003
Objective: To assess the association between duration of breast feeding and measures of adiposity in adolescence. Design: Population based birth cohort study.
Cole, T.J., Treleaven, P., Wells, J.C.K.
core  

Direct vs. Expressed Breast Milk Feeding: Relation to Duration of Breastfeeding

open access: yesNutrients, 2017
Background: Studies examining direct vs. expressed breast milk feeding are scarce. We explored the predictors of mode of breastfeeding and its association with breastfeeding duration in a multi-ethnic Asian population.
W. Pang   +15 more
semanticscholar   +1 more source

Breast Feeding [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1900
n ...
openaire   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Persistent effects of early infant diet and associated microbiota on the juvenile immune system. [PDF]

open access: yes, 2015
Early infant diet has significant impacts on the gut microbiota and developing immune system. We previously showed that breast-fed and formula-fed rhesus macaques develop significantly different gut microbial communities, which in turn are associated ...
Ardeshir, Amir   +5 more
core   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Breast-feeding and cognitive development: a meta-analysis.

open access: yesAmerican Journal of Clinical Nutrition, 1999
BACKGROUND Although the results of many clinical studies suggest that breast-fed children score higher on tests of cognitive function than do formula-fed children, some investigators have suggested that these differences are related to confounding ...
James W. Anderson   +2 more
semanticscholar   +1 more source

A Randomized Controlled Clinical Trial of Olive Oil Added to Human Breast Milk for Weight Gaining in Very Low Birth Weight Infants

open access: yesJournal of Family and Reproductive Health, 2011
Objective: Evaluating the effect of vegetable oil, as a supplement to breast milk in increase the weight gaining of VLBW neonates. Materials and methods: In this single blind; Randomized clinical trials , in NICU of Vali-asr Hospital, Tehran University ...
Elaheh Amini   +5 more
doaj  

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