Results 131 to 140 of about 1,907,433 (308)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Accuracy of abbreviated breast magnetic resonance imaging protocols for primary tumor and post-treatment evaluation

The Egyptian Journal of Radiology and Nuclear Medicine
Background Prompt and accurate detection of breast lesions is essential to improve patient outcomes, particularly in settings with limited access to extensive imaging.
Lina Choridah, Kardinah Kardinah, Vincent Laiman, Zannuba Arifah Noor, Putri Noviantika Laskarsantri, Rozan Muhammad Irfan, Sariningsih Hikmawati   +6 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Positive Predictive Value of Breast Ultrasonography BI-RADS Category 4 and 5 Lesions in One Institution at 2017

, 2019
Purpose: To retrospectively analyze the positive predictive values (PPVs) of the breast lesions classified as categories 4 and 5 by using Breast Imaging reporting and Date System (BI-RADS) ultrasonography (US). Materials and Methods: Between January 2017
박영진, 윤정현, 문희정, 김은경, 김민정, 이시은   +5 more
core  

Genome‐Wide and Multi‐Omics Analysis Identified DNA‐Interacting Circular RNA circFOXK2 as MLL1 Regulator for Histone H3K4 Methylation in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Circular RNA circFOXK2 is frequently upregulated in pancreatic ductal adenocarcinoma to promote tumor heterogeneity, growth, and metastasis. Through circRNA‐DNA interaction at different genomic locations, circFOXK2 removes the PPIE inhibitory effects on MLL1 for gene‐activating H3K4 methylation of the oncogenes.
Chi Hin Wong, Jessica Jazmin Peña‐Paladines, Sum Yin Valerie Leung, Ka‐Fai To, Kenneth Siu Ho Chok, Yangchao Chen   +5 more
wiley   +1 more source

The additive diagnostic value of ultrasonic strain elastography in characterizing BI-RADS 4 breast lesions

The Egyptian Journal of Radiology and Nuclear Medicine
Background Breast cancer is a significant global health issue and is a leading cause of female deaths worldwide. Ultrasonography (US) is an adjunct technique for early diagnosis of breast cancer but has low specificity.
Dalia Bayoumi, Farah Ahmed Shokeir, Rasha Karam, Ghada Hassan Abd Elraouf, Dina Abdallah Ibrahim, Aya Elboghdady   +5 more
doaj   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

The added value of abbreviated MRI with UF DCE-MRI and DWI on digital breast tomosynthesis in diagnosing breast lesions

Digital breast tomosynthesis (DBT) has become a standard screening tool for breast cancer. However, its diagnostic performance is still limited compared to contrast-enhanced MRI, especially in women with dense breasts. Ultrafast dynamic contrast-enhanced
Iima, Mami, Honda, Maya, Ohashi, Akane, Nakamoto, Yuji, Kataoka, Masako, Nickel, Marcel Dominik, Urushibata, Yuta, Förnvik, Daniel, Ohashi, Akane,, Nakamoto, Yuji,, Honda, Maya,, Förnvik, Daniel,, Nickel, Marcel Dominik,, Kataoka, Masako,, Iima, Mami,, Urushibata, Yuta,, Lund University.   +16 more
core   +1 more source

MZF1 Inhibits TGFβ‐1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer

Advanced Science, EarlyView.
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng, Mengxi Huang, Yiting Wang, Hongyu Wang, Haimei Feng, Xiaoming Bai, Jie Chen, Ke Xu, Xiaoyuan Chu, Zengjie Lei   +9 more
wiley   +1 more source

Benign and malignant breast lesions in children and adolescents - diagnostic and therapeutic approach

Frontiers in Pediatrics
Benign and malignant breast lesions in children and adolescents are rare compared to adults. Most tumors are benign. Malignant breast lesions are extremely rare. Fibroadenomas are the most common, accounting for 95% of all lesions.
Patrycja Sosnowska-Sienkiewicz, Danuta Januszkiewicz-Lewandowska, Przemysław Mańkowski   +2 more
doaj   +1 more source