Results 171 to 180 of about 1,907,433 (308)

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Positive Predictive Values (PPV) of Fine Needle Aspiration(FNA) Cytology in Breast Lesions

, 2009
Purpose: To evaluate the positive predictive values (PPV) of breast lesions with suspicious or malignant fine needle aspiration (FNA) cytology. Materials and Methods: From April 2001 to July 2008, 24 patients (age: 18-60, mean: 42.69 yrs) who had ...
김지연, 윤정현, 문희정, 곽진영, 김명현, 김은경, 김민정   +6 more
core  

Development and internal validation of an interpretable mammography-based model for malignancy risk stratification in BI-RADS 4 breast lesions. [PDF]

Front Oncol
Zhang Y, Ding N, Jiao T, Wang B.
europepmc   +1 more source

Dual‐Targeted Biomimetic MoSe2 Nanozymes for Enhancing Peri‐Implant Soft Tissue Integration

Advanced Science, EarlyView.
A dual‐targeting biomimetic nanozyme, MoSe2@SPMM, selectively targets Staphylococcus aureus and oxidatively stressed macrophages. Near‐infrared activation couples contact‐enhanced photothermal bacterial eradication with reactive oxygen species scavenging to disrupt the pathogenic–immunological amplification loop.
Minghao Zhou, Miaomiao Tian, Jingwei Yu, Jiaxin Kang, Miaomiao Chen, Yue Yuan, Lizhi Liu, Hongbo Wei   +7 more
wiley   +1 more source

Clinical observation of ultrasound-guided microwave ablation for 1717 benign breast lesions: a multicenter study. [PDF]

Insights Imaging
Zhou Y, Liu Y, Li H, Wang PY, Wang YF, Li MK, Zheng CF, Xu ZF, Wang SW, Wang HL, Wang SR, Xu D.   +11 more
europepmc   +1 more source

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Surgeon-Performed Point-of-Care Ultrasound in Complex Breast Lesions: Implications for Oncologic Diagnosis and Surgical Planning. [PDF]

Cureus
Najib C, Hamze H, Hteit A, Finianos Y, Nicolas GS, Bou Rizk R, Al Rumhein J, Abou Zahr S, El Hindi A, Manouchakian M, El Hajj A, Tlais M, El Fassih I, Siblini MI.   +13 more
europepmc   +1 more source

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

Advanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu, Yue Xi, Sheng Wang, Ye Chen, Jiajie Yang, Xiaojian Shi   +5 more
wiley   +1 more source

Clinical presentation and epidemiological patterns of breast lesions: Experience from a tertiary care hospital. [PDF]

Bioinformation
Jain C, Shah S, Singh S.
europepmc   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source