The Histopathological Spectrum of Breast Lesions in Bangladeshi Women. [PDF]
Razzaque S +8 more
europepmc +1 more source
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai +15 more
wiley +1 more source
Spectral-habitat analysis and perfusion fingerprinting on contrast-enhanced ultrasound for characterizing tumor perfusion in breast lesions. [PDF]
Liu S +8 more
europepmc +1 more source
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang +18 more
wiley +1 more source
Histomorphological and Immunohistochemical Profile of Malignant Breast Lesions in a Tertiary Care Center of Central India: A Cross-Sectional Study. [PDF]
Himani H, Jain A, Agarwal S, Gangwani A.
europepmc +1 more source
ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang +5 more
wiley +1 more source
Management of high-risk (B3) breast lesions in symptomatic practice: evidence review and practical recommendations for multidisciplinary care. [PDF]
Rakha EA +31 more
europepmc +1 more source
SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian +8 more
wiley +1 more source
Shear Wave Elastography for Characterization of Breast Lesions in Clinical Routine. [PDF]
Kelemen S +6 more
europepmc +1 more source

